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EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients  [cached]
Li SHAN,Yan ZHANG,Feng ZHAO,Limou ZHENG
Chinese Journal of Lung Cancer , 2013, DOI: 10.3779/j.issn.1009-3419.2013.02.04
Abstract: Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in patients with EGFR mutation. However, significant differences in EGFR mutations exist among different ethnic groups. The aim of this study is to investigate the prevalence of EGFR mutations in Uighur lung adenocarcinoma patients by using a rapid and sensitive detection method and to analyze EGFR mutation differences compared with Han lung adenocarcinoma patients. Methods We examined lung adenocarcinoma tissues from 138 patients, including 68 Uighur lung adenocarcinoma patients and 70 Han lung adenocarcinoma patients, for EGFR mutations in exons 18, 19, 20, and 21 by using the amplification refractory mutation system (ARMS) PCR method. The mutation differences between Uighur and Han lung adenocarcinoma were compared by using the chi-square test method. Results EGFR mutations were detected in 43 (31.2%) of the 138 lung adenocarcinoma patients. EGFR mutations were detected in 11 (16.2%) of the 68 Uighur lung adenocarcinoma patients and in 32 (45.7%) of the 70 Han lung adenocarcinoma patients. Significant differences were observed in the EGFR mutations between Uighur lung adenocarcinoma patients and Han lung adenocarcinoma patients (P<0.001). Conclusion Our results indicate that the EGFR mutation in Uighur lung adenocarcinoma patients (16.2%) is significantly lower than that in Han lung adenocarcinoma patients (45.7%).
Scaling limit of the corrector in stochastic homogenization  [PDF]
Jean-Christophe Mourrat,James Nolen
Mathematics , 2015,
Abstract: In the homogenization of divergence-form equations with random coefficients, a central role is played by the corrector. We focus on a discrete space setting and on dimension 3 and more. Completing the argument started in previous work, we identify the scaling limit of the corrector, which is akin to a Gaussian free field.
Social Cohesion and Islamic Radicalization: Implications from the Uighur Insurgency  [PDF]
Tong Zhao
Journal of Strategic Security , 2010,
Abstract: This article starts with a critical review of the current literature on the Islamic radicalization and Uighur insurgency in Xinjiang, pointing out that existing literature focuses too narrowly on certain aspects of the Uighur insurgency, and is insufficient to explain the causal mechanism of the insurgency and Islamic radicalization. Built upon historical evidence, this article uses sociological analysis to explore the structural changes in the Uighur community over the past decades, and demonstrates the importance and effectiveness of social cohesion theory in identifying the key causal variables which underlie and determine the course of Uighur insurgency and Islamic radicalization. The last section of the article offers policy implications on Islamic radicalization prevention at both international and domestic levels, and on how to reduce the negative impact of Islamic radicalism on national security and stability.
HENDIADYOIN IN MODERN UIGHUR TURKISH / YENI UYGUR TüRK ESINDE IKILEMELER
Dr. Sevgi ?ZTüRK
Turkish Studies , 2008,
Abstract: Hendiadyoin an important feature of Turkic is also used inmodern Uighur Turkish. While giving a harmony to the sentence,hendiadyoin enriches and enforces the meaning. So far hendiadyoinhas been handled and searched by many researchers, in this study weexamined nominal hendiadyoin in modern Uighur Turkish in view ofmeaning and structure and compiled the examples. Thus we tried toshow the efficiency and importance of hendiadyoin in modern UighurTurkish.
??境?燕山??的?造型相  [PDF]
地质论评 , 1937,
Abstract: 一小引?下侏??的小坪系和白??末至第三?初的?色岩系?的不整合,?及小坪系岩?因受?烈褶曲和火成活?的?果而致?侧零?支?破碎等?象,吾??席?先生已曾指出?中??南部
Aspects of Sino-Japan Complementary and Alternative Medicine and Development on the Traditional Uighur Medicine  [PDF]
Abdiryim Yusup,Nobuo Yamaguchi
Evidence-Based Complementary and Alternative Medicine , 2009, DOI: 10.1093/ecam/nen012
Abstract: Two consecutive conferences on ‘Sino-Japan Complementary and Alternative Medicine and Development on the Traditional Uighur Medicine’ were held in Xinjiang Medical University on July 3 and Kanazawa Medical University on October 6, 2007. The Vice president Halmurat Upur presided over the meeting and gave congratulatory address on holding of the conference. In order to understand mutually and discuss the possibility of the Uighur Medicine as CAM and the situation of medicine in the global sense, specialist scholars of Traditional Uighur Medicine and postgraduates attended this conference. In the meeting of the CAM, the achievements on the research of Traditional Uighur Medicine were exchanged and warmly discussed. Presentations were made in the consecutive conference.
Correlation structure of the corrector in stochastic homogenization  [PDF]
Jean-Christophe Mourrat,Felix Otto
Mathematics , 2014,
Abstract: Recently, the quantification of errors in the stochastic homogenization of divergence-form operators has witnessed important progress. Our aim now is to go beyond error bounds, and give precise descriptions of the effect of the randomness, in the large-scale limit. This paper is a first step in this direction. Our main result is to identify the correlation structure of the corrector, in dimension 3 and higher. This correlation structure is similar to, but different from that of a Gaussian free field.
An embedded corrector problem to approximate the homogenized coefficients of an elliptic equation  [PDF]
Eric Cances,Virginie Ehrlacher,Frederic Legoll,Benjamin Stamm
Mathematics , 2014,
Abstract: We consider a diffusion equation with highly oscillatory coefficients that admits a homogenized limit. As an alternative to standard corrector problems, we introduce here an embedded corrector problem, written as a diffusion equation in the whole space in which the diffusion matrix is uniform outside some ball of radius $R$. Using that problem, we next introduce three approximations of the homogenized coefficients. These approximations, which are variants of the standard approximations obtained using truncated (supercell) corrector problems, are shown to converge when $R \to \infty$. We also discuss efficient numerical methods to solve the embedded corrector problem.
Duty Cycle Corrector with SAR for DDR DRAM Application
M.RAGAVAN,K.SUGANTHI
International Journal of Advanced Research in Electrical, Electronics and Instrumentation Engineering , 2013,
Abstract: Double Data Rate Dynamic Random Access Memory (DDR DRAM) has become important to develop a low-power high performance DCC(Duty Cycle Corrector) with better duty cycle accuracy. DDR DRAM increases the speed using Successive Approximation Register Duty Cycle Corrector (SAR DCC). The proposed DCC circuit will be implemented in a 0.18- um CMOS process. Here, Adjuster circuit delay line is being modified for low frequency. The main objective of this paper is to achieve fast duty correction . The state-of- the-art DDR DRAM is proposed where a mixed mode DCC. The circuit uses a digital feedback of SAR design process and performance analysis is presented in the paper. The proposed technique will reduce power consumption and speed gets improved in CMOS technology. The entire work can be done by using CADENCE Virtuso.
Quantitative results on the corrector equation in stochastic homogenization  [PDF]
Antoine Gloria,Felix Otto
Mathematics , 2014,
Abstract: We derive optimal estimates in stochastic homogenization of linear elliptic equations in divergence form in dimensions $d\ge 2$. In previous works we studied the model problem of a discrete elliptic equation on $\mathbb{Z}^d$. Under the assumption that a spectral gap estimate holds in probability, we proved that there exists a stationary corrector field in dimensions $d>2$ and that the energy density of that corrector behaves as if it had finite range of correlation in terms of the variance of spatial averages - the latter decays at the rate of the central limit theorem. In this article we extend these results, and several other estimates, to the case of a continuum linear elliptic equation whose (not necessarily symmetric) coefficient field satisfies a continuum version of the spectral gap estimate. In particular, our results cover the example of Poisson random inclusions.
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