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Radiographic, Hematologic and Biochemical Alterations in Peritoneal Fluid after Intraperitoneal Injection of Barium Sulfate and Gastrografin in Rabbit  [cached]
Sardar Jafari-Shoorijeh,Abutorab Tabatabai-Naini,Sara Varzandian,Amin Tamadon
Zahedan Journal of Research in Medical Sciences , 2012,
Abstract: Background: Evaluation of contrast-induced changes in the peritoneal area may reveal the effects of their permeation followed by gastrointestinal perforation. This study aims to compare the radiographic changes and hematological and biochemical parameters of peritoneal fluid and blood after intraperitoneal injection of barium sulfate and gastrografin to the rabbit.Materials and Methods: In this clinical trial, 15 healthy male rabbits were randomly divided into 3 groups. Respectively to each group 10 ml/kg barium sulfate 30%, 10 ml/kg gastrografin, and 10 ml/kg saline was intraperitoneally injected. Before injection and 24 hours after injection, blood samples and peritoneal fluid were collected to measure glucose, total protein, WBC count and pH. Lateral and dorsal-ventral radiography was provided 20 min and 24 hours after contrast injection.Results: After injection of barium sulfate, serum glucose decreased, cell count and blood neutrophil percentage increased, glucose and the percentage of peritoneal fluid lymphocytes decreased (p<0.05). The amount of total protein, cell count and peritoneal fluid neutrophil percentage increased (p<0.05). Gastrografin injection only increased peritoneal fluid total protein (p=0.04). Other blood factors and peritoneal fluid showed no significant changes. In radiographies, barium sulfate remained in abdominal area and rapid absorption of gastrografin was observed.Conclusion: The use of gastrografin has fewer side effects than barium sulfate and is recommended in patients suspected with gastrointestinal perforation.
Squatter Housing in Annaba City-Algeria
Guessoum Djamel Eddine
The Social Sciences , 2013,
Abstract: Squatter housing problem being dispersed in Annaba city, situated in North-East of Algeria, is considered as the major constraint to the city spatial expansion. The disproportionality between population size and squatter houses expansion makes the situation very intricate, especiqlly on social, economic and environment aspects. After the country independence in 1962, the problem of housing was resolved by succession process by hoses left by frensh conquerors. However, by the industrialisation, housing need seems to be more and more serious. Annaba is a good example representing the housing issues in algerian cities. Among them we can introduce: Municipal land speculation, marginalisation, low standard housing, illicit constructions, etc. The abscence of well tought urban policy and inadequated urban legislations are the major causes for the no response to the housing needs in Annaba metropolitan area.
Urban Community, poverty and corruption: the case of Annaba, Algeria  [cached]
Nadji KAHOUA,Lucretia Mariana CONSTANTINESCU
Essachess : Journal for Communication Studies , 2010,
Abstract: The population in the most Mediterranean countries, particularly in Algeria, is concentrated to the urban communities, cities with more or less importance, urban and coastal regions. This trend of rapid growth of the urban communities leads to multiple consequences both economically and socially on the use of resources and their distribution. The urban is the area where cross the resources, the population and the production activities and yours management. To analyze the corruption as a phenomenon triple (economic, social and institutional) through an urban community (as Annaba’s case in this research) it may well prove very fruitful in terms of lessons on this central phenomenon and its impacts in the North African countries.
Hematologic Emergencies  [PDF]
Gianfilippo Nifosì
Open Journal of Internal Medicine (OJIM) , 2016, DOI: 10.4236/ojim.2016.63014
Abstract: Hematological emergencies are defined as acute life-threatening conditions in hematological diseases due to benign blood disorders or hematological malignancies or as a result of its treatment. This article deals of the most common emergencies encountered by hematologists. Emerging clinical situations, predictable or not, are common in the treatment of hematological diseases. However, the rapid development of new targeted drugs in cancer medicine has led to an increase in chronically ill cancer and hematology patients, who are being treated aggressively despite significant comorbidities and higher age. This development will lead to an increase in the number of hematologic emergencies, and these patients will be seen by various specialists. The knowledge of most hematological emergencies is crucial in daily practice. In this review, we discuss the epidemiology, pathophysiology and clinical with an emphasis on the early diagnosis and treatment of these conditions that can significantly affect the patient’s clinical outcome.
Lights and shadows on the management of the dismissed industrial heritage  [cached]
Augusto Vitale
Techne : Journal of Technology for Architecture and Environment , 2012,
Abstract: The extensive industrial dismissal has opened a strategic issue within the broader public and private housing stock. To reuse and manage this dismissed heritage, after decades of new areas invasion policies, new issues based on areas conversion and buildings recovery are today brought to attention; buildings considered by international critics as witnesses of vital processes in West society over the past two centuries. They are however more vulnerable, for the low value the current opinion still confers to them, while the research world has opened a significant and widespread dispute. Therefore some requests for the Cultural Heritage and Landscape Act revision have been advanced which has trivialized the problem in order to include the industrial heritage within the cultural heritage, while it is urgent the redefinition of an ad hoc project status.
FISH Analysis in Hematologic Cancers
Funda S. PALA
Trakya Universitesi Tip Fakultesi Dergisi , 2005,
Abstract: Objectives: Fluorescence in situ hybridization (FISH) is a new technology which is helpful in the identification of chromosomal aberrations that are associated with hematologic malignancies or solid tumors. In this study, we evaluated the results of FISH analyses in patients with hematologic malignancies. Patients and Methods: FISH analyses were performed in bone marrow samples of 36 patients with an initial or confirmed diagnosis of hematologic malignancy. The cells were cultured for 4, 24, 48, or 72 hours depending on the type of disease. The images obtained from each case were processed on a computer with the SPOT RT program. Results: Using locus specific FISH probes, chromosomal translocation at t(9;22) was studied in 24 patients, t(15;17) was studied in 12 patients, t(8;21) and inv 16 t(16;16) were studied in six patients. In patients with an initial diagnosis of chronic myeloid leukemia, t(9;22) was positive in 60% to 90%. The detection of chromosomal aberrations associated with other hematologic malignancies ranged between 3% to 74%. The FISH analysis was also successful in showing decreases in chromosomal aberrations in patients under follow-up. Conclusion: FISH analysis is of particular help in both the initial diagnosis of, and monitoring chromosomal aberrations in the follow-up of hematologic malignancies.
Bio-Indication of Air Quality in the Annaba City (East of Algeria)
Nadia Tlili,Salim Zarrouk,Larbi Boughediri,Fatah Chaoui
Research Journal of Biological Sciences , 2012,
Abstract: The town of Annaba (East of Algeria) is characterized by a very polluted atmosphere, which became a dangerous for the fauna and the plants, the regional planning and environment ministry has installed an of air quality control network , baptized SAMASAFIA which is composed of 4 stations of air quality monitoring: Station 1 (Annaba), station 2 (El Bouni), station 3 (Sidi Amar), station 4 (Airoport). This study consists to use the pollen as bio-indicator of pollution. The pollen of Malus communis (Rosaceae) and Phoenix dactylifera (Arecaceae), have been exposed to air during 24 h inside the 4 stations of SAMASAFIA. The analysis of SAMASAFIA showed the existence of pollution caused especially by the dust (78 g m 24 h 1) notably at EL Bouni sites. The results showed after 24 h of exposure a considerable decrease in germination percentages at EL Bouni (87-37%) with a loss of 50%. This investigation has permited to combine data of the physico-chemical analysis of network SAMASAFIA with the biological data of the pollen viability in order to estimate the air quality.
Bio-Indication of Air Quality in the Annaba City (East of Algeria)
Nadia Tlili,Salim Zarrouk,Larbi Boughediri,Fatah Chaoui
Research Journal of Biological Sciences , 2007,
Abstract: The town of Annaba (East of Algeria) is characterized by a very polluted atmosphere, which became a dangerous for the fauna and the plants, the regional planning and environment ministry has installed an of air quality control network , baptized SAMASAFIA which is composed of 4 stations of air quality monitoring: Station 1 (Annaba), station 2 (El Bouni), station 3 (Sidi Amar), station 4 (Airoport). This study consists to use the pollen as bio-indicator of pollution. The pollen of Malus communis (Rosaceae) and Phoenix dactylifera (Arecaceae), have been exposed to air during 24 h inside the 4 stations of SAMASAFIA. The analysis of SAMASAFIA showed the existence of pollution caused especially by the dust (78 μg m3 24 h-1) notably at EL Bouni sites. The results showed after 24 h of exposure a considerable decrease in germination percentages at EL Bouni (87-37%) with a loss of 50%. This investigation has permited to combine data of the physico-chemical analysis of network SAMASAFIA with the biological data of the pollen viability in order to estimate the air quality.
Pharmacotherapy of Hematologic Malignancies with Tipifarnib
Ioannis Kotsianidis,Evangelia Nakou,Irene Bouchliou
Clinical Medicine : Therapeutics , 2009,
Abstract: The illumination of cellular processes in cancer has revolutionized oncology drug development leading to a shift from non-specific chemotherapy to the selective targeting of tumorigenic signal transduction pathways. Farnesyltransferase inhibitors (FTIs) target proteins needing prenylation for functioning, thus inhibiting a wide variety of molecular targets crucial for cell proliferation and survival. Tipifarnib (R115777, Zarnestra ), a potent and specific inhibitor of Farnesyltransferase, can attain strong inhibition of tumor growth in preclinical models. As a single agent, tipifarnib has demonstrated activity in several hematologic malignancies, namely acute myeloid leukemia, myelodysplastic syndrome, chronic myeloid leukemia and multiple myeloma. However, considering the complexity of the molecular aberrations implicated in the pathogenesis of hematologic neoplasms, it is rather unlikely that monotherapy with tipifarnib will serve as a stand-alone treatment approach. Indeed, improved results have been achieved by combining tipifarnib with other anticancer agents, whereas the first efforts for the identification of molecular predictors of response are reporting intriguing results. Ongoing trials are anticipated to define the exact role of tipifarnib in the treatment of hematologic malignancies.
Zygomycosis in Two Hematologic Cases
M. T. García-Romero,J. García-Méndez,R. Arenas,T. Ferrari-Carballo,J. Chanona-Vilchis,E. Cervera-Ceballos
Case Reports in Infectious Diseases , 2011, DOI: 10.1155/2011/181782
Abstract: Zygomycosis are invasive mould infections, rarely diagnosed in hematologic patients. Most of the cases published are in patients with prolonged neutropenia, along with other risk factors such as the use of prior broad-spectrum antibiotics (including new antifungal agents, such as voriconazole), diabetes mellitus (with or without ketoacidosis), malnutrition, iron overload (with or without the use of deferoxamine). These infections have poor prognosis due to the involvement of vital anatomic structures and late diagnosis. Until recent years, the treatment was based on high doses of amphotericin B plus surgical debridement. Here we present two patients with hematologic diseases (one with leukemia, the second with aplastic anemia) with an impaired immune system and the diagnosis of zygomycosis. The survival of one of them was mainly due to early diagnosis and surgical debridement; unfortunately the second was misdiagnosed as an extensive ecchymosis due to thrombocytopenia and died with CNS involvement.
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