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A Changing Research and Publication Landscape for Biochemistry
Gabor Mocz
Biochemistry Insights , 2012,
Abstract: This introductory editorial hopes to convey three points to its audience. First, it provides an overview of the new, peer-reviewed, open access journal Biochemistry Insights published by Libertas Academica. Second, it summarizes the benefits of open access publishing concepts to the biochemistry community. And third, it takes a brief look at the near future of biochemistry as a fundamental molecular science whose continued advances and latest developments will be the focus of the new journal. Biochemistry Insights looks forward to receiving research articles, review papers, commentaries and letters from all disciplines and specialties of the field.
A Changing Research and Publication Landscape for Biochemistry
Gabor Mocz
Biochemistry Insights , 2008,
Abstract: This introductory editorial hopes to convey three points to its audience. First, it provides an overview of the new, peer-reviewed, open access journal Biochemistry Insights published by Libertas Academica. Second, it summarizes the benefits of open access publishing concepts to the biochemistry community. And third, it takes a brief look at the near future of biochemistry as a fundamental molecular science whose continued advances and latest developments will be the focus of the new journal. Biochemistry Insights looks forward to receiving research articles, review papers, commentaries and letters from all disciplines and specialties of the field.
Evaluation of arguments in research reports  [cached]
Annatjie Botes
Health SA Gesondheid , 2000, DOI: 10.4102/hsag.v5i1.15
Abstract: Some authors on research methodology are of the opinion that research reports are based on the logic of reasoning and that such reports communicate with the reader by advancing logical, coherent arguments (Bvhme, 1975:206; Mouton, 1996.69). *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
COMPARISON OF PREVIOUS REPORTS IN INDOOR PATIENTS-A POTENTIAL TOOL FOR INTERNAL QUALITY ASSURANCE IN CLINICAL BIOCHEMISTRY  [cached]
Parveen Bansal
International Journal of Bioassays , 2012,
Abstract: Laboratory testing is an important and integral part of the decision-making process and strongly influences medical diagnosis and therapies. Normally the extraneous results in a clinical report raise a doubt towards the quality assurance program of a laboratory. This communication is intended to highlight the potential use of previous reports of indoor patient in an indoor hospital laboratory as a tool for quality assurance. In this study approximately 10% of the doubtful reports were picked up randomly and the results were compared with the earlier reports of the patient retrieved from database. The study revealed that there was a significant reduction of more than 80% in the test repeats resulting in decrease in expenses on repeat tests (80%).There was a significant average reduction of time and human resource investment, decrease in the instrument working hours and increased workflow efficiency due to reduction in the test repeats. Moreover there was an increase in the confidence level of consultant towards quality control program and authenticity of the reports.
An Evaluation of Lecturers Perceptions Towards Research
Izah Mohd Tahir,Nor Mazlina Abu Bakar
The Social Sciences , 2013,
Abstract: Teaching and research are two main requirements in the job descriptions of university lecturers. Other requirements in the job descriptions include organizing seminars/conferences, presenting papers at national and international levels, publishing papers/articles in refereed journals, publishing books and other scholarly activities. Through research one could acquire knowledge and disseminate to students as well as peers, which finally contribute to building competitive advantage to the university concerned. The current study reports findings from a survey, which examined the perceptions of university lecturers towards research. The findings indicate that research is essential to professional development motivated by getting promotion and salary increment. They also, shed some light on the main barrier for not doing research among university lecturers-poor statistical and econometric skills. Implications and suggestions for future research are also, provided.
Welcome to Veterinary Medicine: Research and Reports
Musser JMB
Veterinary Medicine: Research and Reports , 2011, DOI: http://dx.doi.org/10.2147/VMRR.S24177
Abstract: Welcome to Veterinary Medicine: Research and Reports Editorial (2850) Total Article Views Authors: Musser JMB Published Date September 2011 Volume 2011:2 Pages 9 - 10 DOI: http://dx.doi.org/10.2147/VMRR.S24177 Musser Jeffrey MB Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, TX, USA This year marks the 250th anniversary of the Royal Veterinary School in Lyon, France, the world's first veterinary college. Since its inception, many changes have occurred in veterinary medicine such as views on education and didactic learning, demographics of our profession, and standards of practice in animal husbandry, medicine, surgery, anesthesia, and vaccinology. In fact, the concept of infectious diseases has changed - remember the germ theory was proposed a mere 140 years ago. However, one constant tenet in our profession has been the need to disseminate progresses, innovations, advances, and developments in veterinary sciences. Published reports are the foundation for the growth of medicine and science. What would the state of medicine be if Pasteur, Koch, Bourgelat, or Theobald Smith had not published their works? Post to: Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter Readers of this article also read: Performance in L1 and L2 observed in Arabic-Hebrew bilingual aphasic following brain tumor: A case constitutes double dissociation Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite Evidence-based decision-making within the context of globalization: A “Why–What–How” for leaders and managers of health care organizations The cognitive basis of diglossia in Arabic: Evidence from a repetition priming study within and between languages "Globalized public health.” A transdisciplinary comprehensive framework for analyzing contemporary globalization’s influences on the field of public health Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology Epigenomics in cancer management DataGenno: building a new tool to bridge molecular and clinical genetics Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer disease
Physiological Responses of Broiler Chickens to Quantitative Water Restrictions: Haematology and Serum Biochemistry  [PDF]
F. C. Iheukwumere,U. Herbert
International Journal of Poultry Science , 2003,
Abstract: The effect of water restriction on haematology and serum biochemistry of broiler chickens was investigated. A total of ninety six 4-week old Anak broiler birds were used for this study. The birds were divided into 4 treatment groups and within each group, replicated three times at 8 birds per replicate. Different quantities of water were fed to the birds as treatments, that is, ad libitum (To), 3.2 liters (T1), 2.2 liters (T2), 1.2 liters (T3) per day in a completely randomized design (CRD) experiment. The results show that the haematological values were significantly influenced (P<0.05) by severity of water restrictions. However, broilers on T3 (1.2 liters of water restriction) showed a higher mean value for white blood cell (WBC), which differed, significantly from To (control) and T1 (3.2 liters of water restrictions). The mean values of the chemical constituents (Na+, K+, Ca++, Cl-, HCO3-) in the sera of the broiler chickens were significantly (P<0.05) influenced by severity of water restrictions. There was no significant difference (P>0.05) for Alkaline phosphatase and Aspartate transaminase enzyme activity but Alanine transaminase showed significant differences (P<0.05) between the treatments. Total protein albumin showed significant (P<0.05) difference between the treatments but serum globulin did not differ significantly (P>0.05) between the treatments.
Quantitative Analysis of Narrative Reports of Psychedelic Drugs  [PDF]
Jeremy R. Coyle,David E. Presti,Matthew J. Baggott
Quantitative Biology , 2012,
Abstract: Background: Psychedelic drugs facilitate profound changes in consciousness and have potential to provide insights into the nature of human mental processes and their relation to brain physiology. Yet published scientific literature reflects a very limited understanding of the effects of these drugs, especially for newer synthetic compounds. The number of clinical trials and range of drugs formally studied is dwarfed by the number of written descriptions of the many drugs taken by people. Analysis of these descriptions using machine-learning techniques can provide a framework for learning about these drug use experiences. Methods: We collected 1000 reports of 10 drugs from the drug information website Erowid.org and formed a term-document frequency matrix. Using variable selection and a random-forest classifier, we identified a subset of words that differentiated between drugs. Results: A random forest using a subset of 110 predictor variables classified with accuracy comparable to a random forest using the full set of 3934 predictors. Our estimated accuracy was 51.1%, which compares favorably to the 10% expected from chance. Reports of MDMA had the highest accuracy at 86.9%; those describing DPT had the lowest at 20.1%. Hierarchical clustering suggested similarities between certain drugs, such as DMT and Salvia divinorum. Conclusion: Machine-learning techniques can reveal consistencies in descriptions of drug use experiences that vary by drug class. This may be useful for developing hypotheses about the pharmacology and toxicity of new and poorly characterized drugs.
Grand challenges in cellular biochemistry: the “next-gen” biochemistry  [PDF]
Cecilia Giulivi
Frontiers in Chemistry , 2014, DOI: 10.3389/fchem.2014.00022
Abstract: It is said that Biochemistry is a young scientific discipline, making its “formal” debut towards the end of the 1900th century (Manchester, 2000), with seminal works by Buchner (Buchner, 1897;Jaenicke, 2007), Hill (Hill, 1898), Harden (Harden, 1911), and, of course, Michaelis and Menten (Johnson, 2013;Michaelis and Menten, 2013;Deichmann et al., 2014). Back in 1896, Buchner’s preparation of a “juice” from yeast (Buchner, 1897) is often regarded as the birth of modern biochemistry. However, I tend to digress with this strict view of biochemistry, reasoning that we (as a species) were taking advantage of biochemical principles without having a deep understanding of the molecular process. For instance, consider Buchner’s “juice” or actually wine making. This method, that has at its core the fermentation process one of the key pathways in biochemistry, dating back to around 6000 BC (Chambers and Pretorius, 2010). Refer to the complicated production of fish sauces considered among the most common flavor-enhancing condiments produced and distributed across ancient Roman Empire (Lowe, 2009). Another example comes from the mixture of organic preservatives (i.e., biochemical) used for ancient Egyptian mummification (Buckley and Evershed, 2001). This early biochemistry was empirical, done in settings other than laboratories, serving immediate needs, and probably passed onto next generations by oral traditions. Then, are these contributions valuable to the genesis of biochemistry? Should they be dismissed because the microorganisms were not genotyped, the reactions were done in dolia instead of microplates? Then, if we accept these very early facts (and why not experiments?) as part of the genesis of this field, we will need to accept that biochemistry is a long, long (ancient?) journey that have accompanied us since the dawn of civilization. The general field of Biochemistry has grown since then to the point that it has been expanded to various more specific areas of research. For example, Cellular Biochemistry is at the crossroads of Chemistry (Organic, Physical, Analytical, Inorganic, Biological) and Biology (Chemical, Molecular) including studies on biomolecular structures and the mechanism of biochemical reactions, but also on the biological purposes of biochemical phenomena, i.e., metabolic pathways and their control, physiological significance and clinical relevance of topics presented. The regulation includes protein and gene expression analyses as well as protein post-translational modifications, epigenetic controls, metabolite-control systems, and
Welcome to Veterinary Medicine: Research and Reports  [cached]
Musser JMB
Veterinary Medicine: Research and Reports , 2011,
Abstract: Musser Jeffrey MBDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, TX, USAThis year marks the 250th anniversary of the Royal Veterinary School in Lyon, France, the world's first veterinary college. Since its inception, many changes have occurred in veterinary medicine such as views on education and didactic learning, demographics of our profession, and standards of practice in animal husbandry, medicine, surgery, anesthesia, and vaccinology. In fact, the concept of infectious diseases has changed - remember the germ theory was proposed a mere 140 years ago. However, one constant tenet in our profession has been the need to disseminate progresses, innovations, advances, and developments in veterinary sciences. Published reports are the foundation for the growth of medicine and science. What would the state of medicine be if Pasteur, Koch, Bourgelat, or Theobald Smith had not published their works?
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