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Romboencefalitis por Listeria monocytogenes: Caso clínico
Bravo M,Mauricio; Ferrer D,Sergio; Trujillo V,Sergio;
Revista médica de Chile , 1998, DOI: 10.4067/S0034-98871998000700011
Abstract: we report a previously healthy 44 years old female, that presented with mild clouding of consciousness, a left cerebellar syndrome, involvement of v, x and xii left cranial nerves and an alteration of epicritic sensitivity in the left half of the body. cerebrospinal fluid had inflammatory features. cerebrospinal fluid and blood cultures were positive for listeria monocytogenes. magnetic resonance imaging disclosed a rhomboencephalitis. antibiotics were started and the clinical condition of the patient improved progressively. after three months of follow up, the patient is notably recovered and there is a regression of hyperintense lesions of the brainstem in the magnetic resonance imaging. the diagnosis of listeria monocytogenes infection must be born in mind in the presence of a rhomboencephalitis.
Romboencefalitis por Listeria monocytogenes: Caso clínico Listeria monocytogenes rhomboencephalitis: Report of one case  [cached]
Mauricio Bravo M,Sergio Ferrer D,Sergio Trujillo V
Revista médica de Chile , 1998,
Abstract: We report a previously healthy 44 years old female, that presented with mild clouding of consciousness, a left cerebellar syndrome, involvement of V, X and XII left cranial nerves and an alteration of epicritic sensitivity in the left half of the body. Cerebrospinal fluid had inflammatory features. Cerebrospinal fluid and blood cultures were positive for Listeria monocytogenes. Magnetic resonance imaging disclosed a rhomboencephalitis. Antibiotics were started and the clinical condition of the patient improved progressively. After three months of follow up, the patient is notably recovered and there is a regression of hyperintense lesions of the brainstem in the magnetic resonance imaging. The diagnosis of Listeria monocytogenes infection must be born in mind in the presence of a rhomboencephalitis.
PATOGENESIS DE Listeria monocytogenes, MICROORGANISMO ZOONOTICO EMERGENTE.
Torres,Kirvis; Sierra,Sara; Poutou,Raúl; Carrascal,Ana; Mercado,Marcela;
Revista MVZ Córdoba , 2005,
Abstract: listeria monocytogenes in addition to being a paradigm for the immunological investigation has become in an appropriate model system to the analysis of the molecular mechanisms of the intracellular parasitism of other bacteria strains. inmunologyst were interested in this microorganism when was recognized as a risky organism for public health and the food industry security. from mid of the 80's scientists have researched the molecular biology of virulence markers of this microorganism, the cellular biology of the interactions of these markers with the receptors of the host cell, the cytoskeleton, the transduction signals routes and the mechanisms of immunity mediated by the host cells. the intention of this review is to describe some taxonomic and phylogenetics characteristics of listeria monocytogenes, the human and animal incidence of several serotypes, the physiopathology of the infection, animals models and cellular culture employed for virulence studies, the risk populations, clinical manifestations of human and animal listeriosis, the treatment, the genetic organization and evolution de the virulence markers, the mechanisms used to interact with the host cell, the mechanism to escape from the cellular death processes and to pass through an infected cell to another one. the compiled information is from great importance for the health personnel, consumers and risk population; reason for which listeria monocytogenes it is a pathogen that represents a threat for world-wide the public health.
Romboencefalitis: una forma de infección por Listeria monocytogenes en el sistema nervioso central
Illanes D,Sergio; Araya C,Pablo; Ferrer D,Sergio; Cartier R,Luis; Bravo M,Mauricio; Castillo C,Sergio;
Revista médica de Chile , 2003, DOI: 10.4067/S0034-98872003000800013
Abstract: listeria monocytogenes infections can involve the central nervous system in the form of a rhomboencephalitis. three possible cases of rhomboencephalitis by listeria monocytogenes are reported (2 females, aged 44 and 49 and a man of 36 years old). the three cases were preceded by an unspecific prodrome of headache, vertigo and fever in absence of a meningeal syndrome. the neurological stage was defined by the unilateral involvement of cranial nerves and the cerebellum and a clear inflammatory cerebrospinal fluid (csf) with the presence of polymorphonuclear leukocytes, and normal glucose and protein levels. a magnetic nuclear resonance (mri) showed the appearance of characteristic images, present in the bulboprotuberancial region. these images are one of the most constant features of this disease, reported in the literature. the early diagnosis of rhomboencephalitis was based on the clinical picture, the study of the csf and the mri, allowing the use of antimicrobials, prior to microbiological identification. therefore, the risk of brain stem and cardiac complications of the disease is reduced (rev méd chile 2003; 131: 921-8)
Patogénesis de Listeria monocytogenes, microorganismo zoonotico emergente
Kirvis Torres,Sara Sierra,Raúl Poutou,Ana Carrascal
Revista MVZ Córdoba , 2005,
Abstract: Listeria monocytogenes además de ser un paradigma para la investigación inmunológica se ha convertidoen sistema modelo apropiado para el análisis de los mecanismos moleculares del parasitismo intracelularde otras bacterias. Investigadores en el área de la inmunología se interesaron en este microorganismocuando se reconoció el riesgo que representaba para la salud pública y la seguridad en la industria dealimentos. Desde mediados de los a os 80’s se ha investigado la biología molecular de los marcadores devirulencia de este microorganismo, la biología celular de las interacciones de los marcadores de virulenciacon los receptores de la célula hospedero, el citoesqueleto, las vías de transducción de se ales y losmecanismos de inmunidad mediada por células del hospedero. El propósito de esta revisión es describiralgunas características taxonómicas y filogenéticas de Listeria monocytogenes , la incidencia humana yanimal de varios serotipos, la fisiopatología de la infección , modelos animales y de cultivo celular utilizadospara estudios de virulencia, las poblaciones de riesgo, manifestaciones clínicas de listeriosis humana yanimal, el tratamiento, la organización genética y evolución de los determinantes de virulencia, losmecanismos empleados para interactuar con la célula hospedera, y los mecanismos para escapar de losprocesos de muerte celular y pasar de una célula infectada a otra. La información recopilada resulta degran importancia para el personal de salud, industria, consumidores y población de riesgo; razón por lacual Listeria monocytogenes es un patógeno que representa una amenaza para la salud pública mundial.
Encefalopatía perdedora de sal en romboencefalitis por listeria Cerebral salt wasting syndrome associated with Listeria monocytogenes encephalitis. Report of one case  [cached]
Jorge Vega,Gonzalo Matamala
Revista médica de Chile , 2013,
Abstract: Hyponatremia is common in patients with severe neurological diseases and is often secondary to a syndrome of inappropriate antidiuretic hormone secretion (SIADH). However, in some patients, hyponatremia is due to cerebral salt wasting syndrome (CSWS). SIADH and CSWS treatments are opposite and misdiagnosis can lead to increased morbidity and mortality. We report a 52 years old female with a rhom-boencephalitis caused by Listeria Monocytogenes (LM), ventriculitis and abscesses in cerebellum and brainstem. It was associated with hyponatremia, hypotension, increased natriuresis, hypouricemia, and low creatinine and blood urea nitrogen levels. Large amounts ofsodium were needed and the condition persisted after hospital discharge. Hyponatremia is common in central nervous system involvement by LM, however we are not aware of CSWS reports of this condition.
Romboencefalitis: una forma de infección por Listeria monocytogenes en el sistema nervioso central Rhomboencephalitis caused by listeria monocytogenes infection: Report of three cases  [cached]
Sergio Illanes D,Pablo Araya C,Sergio Ferrer D,Luis Cartier R
Revista médica de Chile , 2003,
Abstract: Listeria monocytogenes infections can involve the central nervous system in the form of a rhomboencephalitis. Three possible cases of rhomboencephalitis by Listeria monocytogenes are reported (2 females, aged 44 and 49 and a man of 36 years old). The three cases were preceded by an unspecific prodrome of headache, vertigo and fever in absence of a meningeal syndrome. The neurological stage was defined by the unilateral involvement of cranial nerves and the cerebellum and a clear inflammatory cerebrospinal fluid (CSF) with the presence of polymorphonuclear leukocytes, and normal glucose and protein levels. A magnetic nuclear resonance (MRI) showed the appearance of characteristic images, present in the bulboprotuberancial region. These images are one of the most constant features of this disease, reported in the literature. The early diagnosis of rhomboencephalitis was based on the clinical picture, the study of the CSF and the MRI, allowing the use of antimicrobials, prior to microbiological identification. Therefore, the risk of brain stem and cardiac complications of the disease is reduced (Rev Méd Chile 2003; 131: 921-8)
Determinación de Listeria spp: en quesos y embutidos comercializados en Cuba Determination of Listeria spp in cheese and sausages sold in Cuba  [cached]
Tamara Kely Martino Zagovalov,Virginia Leyva Castillo,Anay Pérez Chang,Maritza de los Reyes
Revista Cubana de Salud Pública , 2005,
Abstract: La Listeria monocytogenes es un patógeno emergente causante de una enfermedad transmitida a través de los alimentos conocida como listeriosis, que cursa de forma grave y generalmente deja secuelas en las personas que la sobreviven. La detección de la L. monocytogenes en los alimentos de mayor riesgo, como son los listos para el consumo reviste gran importancia. En el presente trabajo se determinó la incidencia de la Listeria en 54 muestras de quesos y 98 de embutidos y ahumados, comercializados en Cuba. Se aplicó un método tradicional para la detección cualitativa y cuantitativa de la L. monocytogenes según la Norma UNE-EN ISO 11290-1 (1997) y el Draft International Standard ISO/DIS 11290-2 (1995), además se realizaron pruebas bioquímicas adicionales para la identificación de otras especies de Listeria. Para la detección cualitativa de la Listeria también se aplicó una prueba de diagnóstico rápido. La L. monocytogenes se aisló en queso azul, en salchichón y mortadela; la L. innocua: en queso frescal y queso cubanito, en chorizo, longaniza magro y morcilla y la L. welshimeri: en salchichas. Las dos especies halladas en salchichón se encontraron asociadas a una misma muestra. En otras tres muestras (pollo ahumado, chorizo, mortadela) se detectó la Listeria por la prueba rápida, sin lograr el aislamiento por el método tradicional, lo cual se debe a la mayor sensibilidad del primer método. La enumeración resultó < 102 UFC/g de alimento en todos los casos. La utilización de la técnica cualitativa permitió demostrar la presencia de la L. monocytogenes en tres de las muestras analizadas lo cual limita estos productos para su comercialización y consumo Listeria monocytogenes is an emerging pathogen causing a food-borne disease called listeriosis that seriously affects people and generally leaves sequelae in survivors. Detection of L. monocytogenes in high-risk foodstuffs such as ready-to-eat food is overly important. The present paper determined the incidence of Listeria in 54 cheese samples and 98 samples of sausage and smoked products that are sold in Cuba by using a traditional method for qualitative and quantitative detection of L. monocytogenes according to Standard UNE-EN ISO 11290-2 (1997) and Draft International Standard ISO/DIS 11290-2 (1995). Additional biochemical tests for detection of other Listeria species. A rapid diagnostic test was used for qualitative detection. L. monocytogenes was isolated from blue cheese, salami and mortadella samples. L innocua was detected in Frescal and Cubanito types of cheese, chorizo (highly seasoned pork sausage), l
Occurrence of Listeria monocytogenes in salami
Borges, Maria de Fatima;Siqueira, Regina S. de;Bittencourt, Anna Maria;Vanetti, Maria Cristina D.;Gomide, Lúcio Alberto M.;
Revista de Microbiologia , 1999, DOI: 10.1590/S0001-37141999000400012
Abstract: eighty-one samples of four different types of salami (friolan, hamburguese, italian and milanese), belonging to five brands, and purchased at rio de janeiro market, were evaluated for the occurrence of listeria monocytogenes. the pathogen was detected in 13.3% of italian type samples of salami, while l. innocua occurred in 6.5% of the italian type and in 16.6% of the milanese type. the remaining samples were negative for listeria spp.
Occurrence of Listeria monocytogenes in salami  [cached]
Borges Maria de Fatima,Siqueira Regina S. de,Bittencourt Anna Maria,Vanetti Maria Cristina D.
Revista de Microbiologia , 1999,
Abstract: Eighty-one samples of four different types of salami (Friolan, Hamburguese, Italian and Milanese), belonging to five brands, and purchased at Rio de Janeiro market, were evaluated for the occurrence of Listeria monocytogenes. The pathogen was detected in 13.3% of Italian type samples of salami, while L. innocua occurred in 6.5% of the Italian type and in 16.6% of the Milanese type. The remaining samples were negative for Listeria spp.
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