文章

    Hnisz, D., Weintraub, A.S., Day, D.S., Valton, A.L., Bak, R.O., Li, C.H., Goldmann, J., Lajoie, B.R., Fan, Z.P., Sigova, A.A., Reddy, J., Borges-Rivera, D., Lee, T.I., Jaenisch, R., Porteus, M.H., Dekker, J. and Young, R.A. (2016) Activation of Proto-Oncogenes by Disruption of Chromosome Neighborhoods. Science, 351, 1454-1458. https://doi.org/10.1126/science.aad9024

被如下文章引用:

  • TITLE: Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis
  • AUTHORS: Gao-De Li
  • KEYWORDS: Chromatin Configuration, Oncogenesis, 3D Genome, Cancer, Cell Differentiation, Cell Cycle, Gene Regulation, Gene Activity
  • JOURNAL NAME: Open Access Library Journal DOI: 10.4236/oalib.1105185 Feb 01, 2019
  • ABSTRACT: More than 30 years ago, we published a paper entitled as “Abnormal Chromatin Configuration and Oncogenesis”, which proposed the first hy-pothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis are presented.