文章

    Mazumdar, C., Shen, Y., Xavy, S., Zhao, F., Reinisch, A., Li, R., Corces, M.R., Flynn, R.A., Buenrostro, J.D., Chan, S.M., Thomas, D., Koenig, J.L., Hong, W.J., Chang, H.Y. and Majeti, R. (2015) Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell, 17, 675-688. https://doi.org/10.1016/j.stem.2015.09.017

被如下文章引用:

  • TITLE: Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis
  • AUTHORS: Gao-De Li
  • KEYWORDS: Chromatin Configuration, Oncogenesis, 3D Genome, Cancer, Cell Differentiation, Cell Cycle, Gene Regulation, Gene Activity
  • JOURNAL NAME: Open Access Library Journal DOI: 10.4236/oalib.1105185 Feb 01, 2019
  • ABSTRACT: More than 30 years ago, we published a paper entitled as “Abnormal Chromatin Configuration and Oncogenesis”, which proposed the first hy-pothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis are presented.