文章

    Dowen, J.M., Fan, Z.P., Hnisz, D., Ren, G., Abraham, B.J., Zhang, L.N., Weintraub, A.S., Schujiers, J., Lee, T.I., Zhao, K. and Young, R.A. (2014) Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes. Cell, 159, 374-387. https://doi.org/10.1016/j.cell.2014.09.030

被如下文章引用:

  • TITLE: Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis
  • AUTHORS: Gao-De Li
  • KEYWORDS: Chromatin Configuration, Oncogenesis, 3D Genome, Cancer, Cell Differentiation, Cell Cycle, Gene Regulation, Gene Activity
  • JOURNAL NAME: Open Access Library Journal DOI: 10.4236/oalib.1105185 Feb 01, 2019
  • ABSTRACT: More than 30 years ago, we published a paper entitled as “Abnormal Chromatin Configuration and Oncogenesis”, which proposed the first hy-pothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis are presented.