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Clinical and histopathological features of orbital granular cell tumor: case report

DOI: 10.1590/S0004-27492012000200014

Keywords: orbital neoplasms [diagnosis], exophthalmos, tomography, x-ray computed, case report.

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Abstract:

a 53 year-old woman presented with a slowly progressive, painless proptosis os. computed tomography disclosed a round, homogeneous, well-delimited lesion in the inferior-temporal orbit. the tumor was composed of round cells with eosinophilic granular cytoplasm. some of the cells had larger eosinophilic granules surrounded by a clear halo; known as pustulo-ovoid bodies of milian or bangle bodies. the diagnosis of a granular cell tumor was then established and confirmed by immunohistochemistry. granular cell tumors are uncommon benign soft tissue neoplasms that have a predilection for the head and neck region. awareness of the typical histopathological features is crucial for the correct diagnosis.

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