treatment of patients with proximal vein thrombosis with low molecular weight heparins is effective and safe. so it allows "hospital at home" care. among low molecular weight heparins tinzaparin is given once daily, making the compliance easier. the twenty patients with deep vein thrombosis who were assisted in the "hospital at home" unit of the clínica nuestra se？ora de la concepción in madrid from december 1999 to december 2000. the mean of age was 71 + 15. the most frequent risk factors were surgery in past three months (19%), known tumour (15%) and previous venous thrombosis (15%). eighteen patients were treated with tinzaparin. no patients showed adverse effects nor complications. low molecular weight heparins, specially tinzaparin, are a safe and effective treatment for deep vein thrombosis in our unit.