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Global Stability of a SLIT TB Model with Staged Progression

DOI: 10.1155/2012/571469

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Abstract:

Because the latent period and the infectious period of tuberculosis (TB) are very long, it is not reasonable to consider the time as constant. So this paper formulates a mathematical model that divides the latent period and the infectious period into n-stages. For a general n-stage stage progression (SP) model with bilinear incidence, we analyze its dynamic behavior. First, we give the basic reproduction number . Moreover, if , the disease-free equilibrium is globally asymptotically stable and the disease always dies out. If , the unique endemic equilibrium is globally asymptotically stable and the disease persists at the endemic equilibrium.

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