Although several studies showed the efficacy and safety from this procedure, the comparative assessment of adipose tissue by cryolipolysis has not been studied until now. Therefore we investigated the quantitative change of cross sectional areas of abdominal SAT (subcutaneous adipose tissue) and VAT (visceral adipose tissue) following cryolipolysis. A prospective study for twelve subjects with a single session of cryolipolysis on abdomen was performed. We assessed for their height, weight, and waist circumferences, body contours by photographs, and the cross sectional areas of visceral and subcutaneous adipose tissues were measured at umbilicus level by computerized tomography for 2 months. The cross sectional areas in SAT reduced from 243.3 ± 24.7 to 238.5 ± 40.7 cm2 at 2 months post-treatment. Those of VAT reduced from 141.3 ± 46.4 to 125.1 ± 42.8 cm2 at 2 months post-treatment. Cross sectional areas of VAT, and waist circumferences were significantly reduced by 16.2 cm2, 4.1 cm respectively. Additionally visual improvement without unexpected adverse events was noted. In conclusion a single session cryolipolysis demonstrated to reduce visceral adipose tissue as well as waist circumferences tissue for 2 months. Further controlled study would be needed to evaluate for reduction of visceral adipose tissue by cryolipolysis.
Klein, S., Fontana, L., Young, V.L., et al. (2004) Absence of an Effect of Liposuction on Insulin Action and Risk Factors for Coronary Heart Disease. The New England Journal of Medicine, 350, 2549-2557.
Manstein, D., Laubach, H., Watanabe, K., Farinelli, W., Zurakowski, D. and Anderson, R.R. (2008) Selective Cryolipolysis: A Novel Method of Non-Invasive Fat Removal. Lasers in Surgery and Medicine, 40, 595-604. https://doi.org/10.1002/lsm.20719
Coleman, S.R., Sachdeva, K., Egbert, B.M., Preciado, J. and Allison, J. (2009) Clinical Efficacy of Noninvasive Cryolipolysis and Its Effects on Peripheral Nerves. Aesthetic Plastic Surgery, 33, 482-488. https://doi.org/10.1007/s00266-008-9286-8
Hu, F. (2008) Measurements of Adiposity and Body Composition. In: Hu, F.B., Ed., Obesity Epidemiology, Oxford University Press, New York, 53-83. https://doi.org/10.1093/acprof:oso/9780195312911.003.0005
Ferraro, G.A., De Francesco, F., Cataldo, C., Rossano, F., Nicoletti, G. and D’Andrea, F. (2012) Synergistic Effects of Cryolipolysis and Shock Waves for Noninvasive Body Contouring. Aesthetic Plastic Surgery, 36, 666-679. https://doi.org/10.1007/s00266-011-9832-7
Sajjadi, A.Y., Manstein, D. and Carp, S.A. (2017) Measuring Temperature Induced Phase Change Kinetics in Subcutaneous Adipose Tissues Using near Infrared Spectroscopy, MR Imaging and Spectroscopy and OCT. Scientific Reports, 7, Article No. 17786.
Shek, S., Chan, N. and Chan, H. (2012) Non-Invasive Cryolipolysis for Body Contouring in Chinese—A First Commercial Experience. Lasers in Surgery and Medicine, 44, 125-130. https://doi.org/10.1002/lsm.21145
Sun, Z., Yang, Y. and Liu, J. (2013) Alternative Cooling and Heating as a Novel Minimally Invasive Approach for Treating Obesity. International Journal of Thermal Sciences, 64, 29-39. https://doi.org/10.1016/j.ijthermalsci.2012.08.003