目的：建立金果榄药材的UPLC指纹图谱，为金果榄药材的质量控制提供依据。方法：采用超高效液相色谱法。色谱条件：色谱柱：Acquity UPLC？BEN C18 (2.1 × 100 mm，1.7 μm)；流动相A：乙腈；流动相B：0.3%磷酸溶液；流速：0.25 ml/min；检测波长：225 nm；柱温：25℃。结果：建立了10批金果榄药材的指纹图谱。金果榄药材有7个共有峰，多数峰可以达到较好分离，具有较高的相似度。结论：建立的超高效液相指纹图谱有较好的精密度、重复性和稳定性，可作为金果榄质量评价参考。
Objective: To establish UPLC fingerprint of Tinospora sagittata and T. capillipes which is expected to provide standards for the quality control and identification of the Chinese crude drug. Method: The UPLC method was used. Chromatography conditions were Acquity UPLC？BEN C18 (2.1 × 100 mm, 1.7 μm) column with gradient mobile phase of acetonitrile and 0.3% phosphate acid. UV detection wavelength was 225 nm, the flow rate was 0.25 ml/min and the column temperature was 25？C. Result: UPLC fingerprints of 10 samples of Tinospora sagittata and T. capillipes were established. 7 mutual peaks were selected as the fingerprint peaks in the samples. Among the obtained fingerprints, most of the detected peaks were separated effectively. 10 samples had higher simi-larities. Conclusion: The established UPLC fingerprint has desirable accuracy, repeatability and sta-bility, which can be used as reference for the quality control of Tinospora sagittata and T. capillipes.