Comparative analysis of epigenetic
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was conducted. We focus on the promoter regions of the whole genomes as well as
oncogenes. Our results revealed that obvious differential histone modifications
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region in both Dnd41 cell lines and K562 cell lines. H3K27ac and H3K4me1 have high
correlation between the two cell lines of oncogenes. Similar results were also achieved
in the promoter region of high expression genes in the Jurkat and K562 cell lines
based on RNA-seq data. This suggests that H2K27ac and H3K4me1 are active regulators
in leukemia cell lines.
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