This research aims to describe the root cause of ecological crisis happening at the moment in terms of the cosmological-metaphysical views, by doing research on the thoughts of a classical Muslim philosophical scientist group in 10th century AD called Ikhwan al-Safa’. To the author, Ikhwan al-Safa’ has a clear idea in viewing the universe holistically and intact as it is. Actually, this non-reductive view was the typical main feature of medieval Islamic classical thought. However, the main reason of choosing the works of Ikhwan al-Safa’, especially their magnum opus Rasa’il Ikhwan al-Safa ’,in the research is that Ikhwan al-Safa’ has put a lot of attention on the “wisdom of universe” in the ontological and epistemological structure of knowledge that were developed in their work. With the main concepts such Love of Universe and Soul of Universe, Ikhwan al-Safa’ have given a holistic vision about the wisdom of the universe and the wisdom of the environment itself.