trachomatisinfection is an important preventable cause of infertility. In
women, up to 70% of genital infection withChlamydia trachomatisare
asymptomatic. In the management of infertility patients, a lot of clinicians or
centres do not routinely screen forChlamydia trachomatisinfection.
Hence all patients being investigated for infertility may potentially be at
risk of tubal blockage in addition to non-tubal factor aetiology. Those with
primary tubal blockage also are at risk of worsening of the blockage.
Objective: To determine if there is a relationship between IgG and IgM
Chlamydia antibody testing (CAT) and tubal factor infertility. Design: It was a
cross sectional descriptive study. Method: The sera of 400 consecutive
consenting infertile patients presenting to the gynaecological clinic of the
Ahmadu Bello University Teaching Hospital, Zaria, Northern Nigeria were tested
for Chlamydia antibodies using ELISA IgG and IgM kits produced by Diagnostic
Automation, Inc., 23961 Craftsman Road, Suite D/E/F, Calabasas, CA 91302, USA. Results:
Up to 264 (66%) of the patients had tubal factor, 64 (16%) had uterine, 56
(14%) had ovarian, 50 (12.5%) had male while 40 (10%) had others. The causative
factors were not mutually exclusive. The sero-prevalence of IgG and IgMChlamydia trachomatis
Posada, C., Jonasson, J., et al. (1992) Prevalence of Urogenital Chlamydia Trachomatis Infection in EL-Salvador— Infection during Pregnancy and Perinatal Transmission. International Journal of STD & AIDS, 3, 33-37.
Moussavi, Z. and Behrouzi, R. (1996) The Prevalence of Chlamydia Infection among Pregnant Women Referred to Perinatal Clinics of Tehran University of Medical Sciences in IRAN. 25th Congress of Medical Women’s International Association. http://www.regional.org.au/au/mwia/papers/full/20_moussavi.htm
Isibor, J.O., Ugbomoiko, D., et al. (2005) Detection of Chlamydia Antigen in Cervical Specimens from Antenatal Clinic Attendees in Benin City, Nigeria. African Journal of Clinical and Experimental Microbiology, 6, 208-211.
Haggerty, C.L., Gottlieb, S.L., Taylor, B.D., Low, N., Xu, F. and Ness, R.B. (2010) Risk of Sequelae after Chlamydia Trachomatis Genital Infection in Women. The Journal of Infectious Diseases, 201, S134-S155.
Tukur, J., Shittu, S.O. and Abdul, A.M. (2006) A Case Control Study of Active Genital Chlamydia trachomatis Infection among Patients with Tubal Infertility in Northern Nigeria. Tropical Doctor, 36, 14-16.
Omo-Aghoja, L.O., Okonofua, F.E., Larsen, U. and Bergstrom, S. (2007) Association of Chlamydia trachomatis Serology with Infertility in Nigerian Women. Journal of Obstetrics and Gynaecology Research, 33, 688-695.
Cooke, I.D. (2007) The Globalization of Reproductive Technology. In: Kruger, T.F., van der Spuy, Z. and Kemper, B.D., Eds., Advances in Fertility Studies and Reproductive E Medicine, Cape Town Juticalpa, 234-240.