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COMPOSITION AND BIOLOGICAL ACTIVITY OF THE ESSENTIAL OIL OF PERUVIAN LANTANA CAMARA

Keywords: Antibacterial , antioxidant , anti-inflammatory , carvone , 13C-NMR , essential oil composition , GC-MS , Pantana cámara , limonene , Verbenaceae

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Abstract:

The composition of the essential oil from Pantana cámara L. (Verbenaceae) obtained by hydrodistillation of the aerial parts was examined by GC, GC/ MS, and 13C-NMR. The GC analysis showed that carvone is the most abundant monoterpene 75.9%, together with limonene 16.9%, accounting for 92.8% of the oil. The major components were also tested by "C-NMR analysis of the essential oil. The L. cámara oil was assayed against several microorganisms, showing moderate antibacterial activity against the human pathogen Staphylococcus aureus (MIC 200 μg/ml). High antioxidant activity evaluated by the Trolox equivalent antioxidant capacity assay (TEAC) was found (29.0 mmol Trolox/kg) and relative low anti-inflammatory activity due to its weak ability for inhibiting lipoxygenase (IC50 = 81.5 μg/ml).

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