Ayurvedic medicine Panchsakar Churna is a combination of simple and routine use herbs even then their combined effect is great in managing constipation, haemorrhoids and pain in abdomen, flatulence, assimilatory disorder and rheumatic conditions. Through the Ayurvedic powder formulation enjoys great reputation, its standardization and quality control parameters are not well defined. The efforts have been initiated to develop certain methods and parameters for standardization and quality control. In house preparations (thee batches) of churna were prepared as per Siddhayog sangrah and the preparations are standardized according to guidelines of World Health Organization. viz extractive value, ash value, phytoconstituents, micromeritic parameter, volatile oil content etc. The results were found in close proximity of three batches. This study on Panchsakar churna was reproducible, precise and may be considered as a method for its quality control.