Microwave reactions are based on the basic principles of green chemistry, basically involve “Go Green” concept. Purpose of green synthesis is to proceed with all the synthetic procedures which are ecofriendly and economic. Great deal of better yield in lesser time than conventional methods are observed. In medicinal chemistry, 1,2,4- triazoles are the source for potent medicaments for different pharmacological activities. In connection with this, literature is being compiled up for the sake of synthesis of 1,2,4- triazoles derivatives by using microwave irradiations.