India has a very rich tradition of indigenous and health care practices. Most of these practices are unique and known to a very few individuals or communities. Such ethno botanical knowledge needs documentation and research validation. There are many strong ethno medicinal claims which later on led to novel drug discovery all over the globe. Leonotis nepetifolia (L.) R. Br. belonging to Lamiaceae family, native to Southern India and tropical Africa is used by tribals and folklore traditions in India. This paper is an attempt to collect, review and analyse all ethnomedicinal claims of the plants reported in India.