A local geochemical soil survey was carried out for the exploration of uranium deposits in the area of north – east Vogelkop Irian Jaya, Indonesia. The study explores the use of trace elements associations as an indicator for the possible presence of uranium deposits. This selective association of trace elements is useful since radon, helium or any other gaseous daughter product of uranium can not be used, as there are no known uranium deposits in the area. Hence no local ore samples are available to establish the inter-elemental association as a guide. To establish the trace elements association in ores, known uranium deposits from different parts of the world are investigated. Fifteen ore samples are analyzed by Instrumental Neutron Activation Analysis (INAA) for their total metal content. The comparative study of elemental association, established for these 15 ore samples with the elemental association shown by the soil is non-representative of the ore types that could be expected in such a geological environment. This study does not indicate the accurrence of local ore, however the geological set up in the area provides the environments in which granitic uranium deposits can occur.