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Miniature as a hypothetical regulatory protein of the Bursicon/Rickets signaling cascade in the wing epithelia of Drosophila melanogaster

Keywords: bursicon , Rickets , Miniature , Dusky , wing maturation

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Abstract:

Soon after eclosion, epithelial cells of the Drosophila wing undergo a number of the processes due to a release of the neurohormone bursicon and its further binding to the GPCR Rickets, collectively referred to as wing maturation. Here we propose hypothetical models of the interaction between extracellular Miniature, and also Dusky, proteins and proteins responsible for triggering of the wing maturation processes in Drosophila melanogaster.

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