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Antinociceptive and antipyretic activities of Amaranthus viridis Linn. in different experimental models

DOI: 10.2298/abs1002397k

Keywords: Amaranthus viridis , antinociceptive activity , acetic acid writhing test , hot plate test , antipyretic activity

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Abstract:

The methanolic extract of the whole plant extract of Amaranthus viridis L (MEAV) was screened for antinociceptive activity using the acetic acid writhing test, hot plate test and tail immersion test in mice and for antipyretic activity using the yeast-induced pyrexia method in rats, at doses of 200 and 400 mg/kg body weight. Significant (p<0.01) dose-dependent antinociceptive and antipyretic properties were observed with 200 and 400 mg/kg.

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