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Association of lower cranial nerve schwannoma with spinal ependymoma in ? NF2.

Keywords: Adolescent , Cranial Nerve Neoplasms , complications , Ependymoma , complications , Human , Male , Neurilemmoma , complications , Neurofibromatosis 2 , complications , Spinal Cord Neoplasms , complications

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A 15 year old male, who had earlier been operated for intraspinal intramedullary ependymoma, subsequently developed a right cerebello pontine (CP) angle mass. A diagnosis of right CP angle ependymoma was considered, in view of established histology of previously operated spinal lesion. Histopathological examination of the well defined extra-axial mass, which was attached with ninth cranial nerve, however revealed a schwannoma. A diagnosis of Neurofibromatosis-2 (NF2) is strongly suspected, because of well established fact, that the spinal ependymomas may have association with lower cranial nerve schwannomas in NF2. Cranial and spinal MRI screening for early diagnosis of associated, asymptomatic lesions, in suspected cases of NF2, particularly in children, is recommended.


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