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ALLOXAN INDUCED DIABETIC RATS

Keywords: Diabetes Mellitus , Dietary fibre , Serum glucose , Serum lipids

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Abstract:

A total of 8 mixed-sex albino rats were made diabetic by injecting 5 percent alloxan interperitonially. Ratswere divided into two groups of 4 rats each and fed separately on non-fibrous and 5% wheat bran supplementedfibrous diets for one month. Results revealed that fibre-fed rats gained less weight as compared to non-fibregroup. Serum glucose level decreased 54.5 percent, triglycerides 29.2 percent, cholesterol 16.26 percent inrats on fibrous diet, while non-fibrous group of rats showed non-significant changes. Faecal cholesterol levelin fibre fed rats was 69.09 percent, while non-fibrous group of rats showed negligible concentration of faecalcholesterol.

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