The purpose of this study is to develop a framework for the accreditation of higher open and distance learning (ODL) programs in Turkey. The study was designed as a sequential monomethod multistrand mixed model including two strands which were both qualitative (QUAL→QUAL). In the first strand, both quantitative and qualitative data were collected through a three-round Delphi study with an expert panel consisting of 28 experts. In the second strand, qualitative data were collected via focus group interview. Based on a comprehensive literature review and the findings from the study, a framework was proposed including an initial accreditation process for new ODL programs and a re-accreditation process for ongoing programs. In addition, 35 criteria for new programs and 42 criteria for ongoing programs were developed to be used in the accreditation process.