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Pesquisaje de anticuerpos contra el virus linfotrópico de células T humanas tipo I (HTLV-I) en donantes de sangre y grupos de riesgo

Keywords: ANTICUERPOS HTLV-BLV , DONADORES DE SANGRE , GRUPOS VULNERABLES , ELISA , WESTERN BLOTTING. , HTLV-BLV ANTIBODIES , BLOOD DONORS , RISK GROUPS , ENZYME-LINKED IMMUNOSORBEENT ASSAY , BLOTTING , WESTERN

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Abstract:

Se estudió la presencia de anticuerpos contra el virus linfotrópico de células T humanas tipo I (HTLV I) en 3 774 sueros; de ellos, 1 409 eran de donantes de sangre, 1 444 de pacientes que habían padecido recientemente alguna enfermedad de transmisión sexual (ETS) y 921 de enfermos politransfundidos. Se emplearon los sistemas DAVIH HTLV I (ELISA) y DAVIH BLOT HTLV I (Western Blot) producidos en Laboratorios DAVIH (La Habana, Cuba), para el pesquisaje y confirmación, respectivamente. De los 68 sueros reactivos en la prueba de ELISA, en 2 se confirmó la presencia de anticuerpos al HTLV I/II y 12 fueron considerados indeterminados por el Western Blot. It was studied the presence of HTLV-I antibodies in 3 774 sera, 1 409 of them were from blood donors, 1 444 were from patients who had suffered from some sexually transmitted disease recently, and 921 from transfused patients. The DAVIH HTLV I (ELISA) and DAVIH BLOT HTLV I (Western Blot) systems produced at the DAVIH Laboratories (Havana, Cuba) were used for screening and confirmation, respectively. Of the 68 reactive sera utilized in the ELISA test, it was confirmed the presence of HTLV I/II antibodies in 2, whereas 12 were considered as undetermined by the Western Blot.

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