All Title Author
Keywords Abstract


Research: ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF Hedera helix LEAF EXTRACT

Keywords: Hedera helix , Analgesic activity , Anti-inflammatory activities , Egg albumin.

Full-Text   Cite this paper   Add to My Lib

Abstract:

The methanolic extract of the leaves of Hedera helix L. (Araliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P<0.05) in the tail flick/ hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20mg/kg and indomethacin 50mg/kg respectively). These findings suggest that the methanol leaf extract of Hedera helix L. possess analgesic (which might have been peripherally mediated) and anti-inflammatory activities; and may lend credence to the ethnomedical claim of the use of the plant for the management of pain and inflammatory conditions.

Full-Text

comments powered by Disqus