Considering the improvment of technology and development in medical and basic medical science. Continuation of learning in community are necessary. The method is to create a cooperative learning environment for students. Students support in exprience, past information about subject reaction and holistic theory and practice helping notice, problem based learning bridge between theory and practice step intervention strategies P.B.L. which include eight steps: helping problem definition, Data collection, problem formulation, intervention, Assessment of learning needs, independent study, Reporting back review of in dependent study, in this paper, this method was investigated with some examples . Using this method in education of science , particularly medical science will improve the translation of science in education and producing science in research.