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January 2013 sleep journal club

Keywords: sleep apnea , sleep study , pulmonary hypertension , pulmonary artery hyptertension , hypoxemia , nocturnal desaturation , continuous positive airway pressure , CPAP , obstructive sleep apnea , central sleep apnea

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Abstract:

No abstract available. Article truncated at 150 words. Jilwan FN, Escourrou P, Garcia G, Ja s X, Humbert M, Roisman G. High occurrence of hypoxemic sleep respiratory disorders in precapillary pulmonary hypertension and mechanisms. CHEST. 2013;143(1):47-55. This is important study that highlights the interaction of pulmonary hypertension (PH) and hypoxemia with complications of sleep disordered breathing. The study intent was to delineate the mechanism of the hypoxemia. There is a well- known association between hypoxemia at night and pulmonary hypertension but the prevalence in studies has been variable. Sleep disordered breathing is also associated with PH but is generally thought to contribute little to the pathogenesis of the PH. Methods: 47 patients were entered into the study with 2/3 of patients having idiopathic PH and 1/3 chronic thromboembolic PH. All the chronic thromboembolic PH patients had undergone thromboendarterctomy or had lesions that were inoperable. Most of the patients were in NYHA class 2 or 3 and were stable on …

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