Introduction: This study was aimed to evaluate the technical efficiency of Hamadan University of Medical Sciences and functional indexes based on using mathematical model analysis of inclusive data (DEA) in 2010.Material and Methods: This study is a cross – sectional, the data field of library and information through the use of doctoral dissertations and master and go directly to the hospital and the University's center for statistics. This method has limitations in dealing method using data envelopment analysis (DEA) to evaluate the technical efficiency of hospitals DEAP2 prescription coverage has been Hamadan University of medical sciences. The model used in this study analysis of multistage DEA model is used for the minimization of production factors and output variables.Results: Data inputs include the number of groups of physicians (general practitioners, specialists, doctors intern in teaching hospitals, physician residents in teaching hospitals), the number of nurses (nurses, nurse aid, nurse), the number of staff and beds and the output includes the number of surgeries, number of ambulatory patients, the percentage of occupied beds, average bed day stay patient is hospitalized. Then calculate the technical efficiency of hospitals and hospital efficiency (efficiency coefficient E=1) and the inefficient (the unit) is obtained.Discussion: The most important factors for technical efficiency in hospitals have been incorrect use of beds patient-day in sufficiency and bed-days occupied. Finally in Hamadan average surplus factor (input), respectively: 3 physician, 9 nurses, 8 other personnel and 3 active beds and there should be surplus production factors surplus to be removed to hospitals in the province average to reach the desired level of technical efficiency. The findings in this study shows the highest ratio of technical efficiency in Besat, Beheshti, Farshchian, Imam Hussein Malayer, ValiAsr Razan, Ali Moradian and Heydari Nahavand, Ghaem and Amiralmomenin Asadabad hospitals in comparison with other hospitals is.