Introduction: Autism is a lifetime developmental disability that determines with sever problem in social relations, communication and behavior. Regarding social interaction difficulties of these children and weakness of social skill interventions in creation of motivation. In this study we tried to examine effect pivotal response treatment method on social skill of autistic children.Material & Methods: In this randomized control trial (RCT) study, according to inclusion and exclusion criteria, 30 autistic participants (6 to 11 years old) that matched based on age, gender and mean length utterance, from especial clinics of Hamedan’s autistic persons selected and placed randomly in one of groups of intervention and control. Sessions was administered individually, lasting for 60 minutes and 2 days a week for 3 months. Both groups of children were tested before and after intervention by CCC (children’s communication checklist) to assess social skill. Data analysis was done through descriptive statistics tests and covariance analysis.Results: Findings of study showed (according to covariance analysis between before and after of intervention in two groups) there is significant changes in social skill’s ability in intervention group.Conclusion: The result of these study indicated effect of pivotal response treatment on social skills in autistic children, therefore this method recommended for speech and language pathologist.