In this paper some problems of public-private partnership in health care system have been investigated. It has been found out that public-private partnership should be considered as an innovative juridical economic model of the public sector. This article provides the analysis of current Ukrainian health care system, which indicates its low effectiveness due to the fact it is based on "Semashko" system. The comparative analysis of health care sectors in Ukraine and Europe has demonstrated that every country modernizes its health care system as well as its financing system in accordance with a number of output parameters: country's budget, possible health care expenditures, availability of infrastructure, morbidity, general social welfare, historical background. The investigated extent of public-private partnership in leading European countries indicates that the use of this mechanism proved to be effective for development of systemic infrastructure sectors. Moreover, it turned out to be effective and important tool to overcome the existing problems of health care system. The interaction of state and private sectors within health care system is likely to ensure prompt and effective implementation of social and medical projects, which in turn are expected to improve the level of medical care quality and social infrastructure and to facilitate the effective development of public medical institutions. In addition, the economic effect resulted from this implementation will reduce budget expenditures and social problems in Ukraine.