Human Immunodeficiency Virus (HIV) is RNA virus that causes Acquired Immune Deficiency Syndrome (AIDS). In Ghana the AIDS epidemic is spreading very fast in densely populated areas with higher numbers of cases occurring in the southern regions especially the densely populated capitals such as Kumasi, Koforidua and Accra as well as mining towns like Obuasi and Tarkwa, and in border towns. Data was collected from Accra and Kumasi on socio-economic backgrounds such as age, sex, education, marital status, household size, among others with a structured questionnaire and analysed using statistical Package for Social Sciences (SPSS) version 16.0. About 72% females and 28% males were interviewed with close to 74% lying between 22 to 40 age brackets. Also 63% of these completed JHS/Middle school, Seventeen (36.1%) are married people, 15 (31.9%) widowed. Majority of them are Akans who are also Christians with different denominations. Among these people, 20 (42.6%) of them are unemployed, and 3 (6.4%) claimed to be self-employed in various disciplines. Most of them said they use condoms as contraceptives in order to prevent the spread of the disease. Income level of the respondents predominantly lies between GH￠50.00- GH￠450.00 per annum. Some of the interventions for preventing the disease include promoting abstinence and faithfulness, promoting reductions in the number of sexual partners, encouraging delays in the onset of sexual activity among others.