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Estudo comparativo de anticorpos IgG e IgE antileishmania como marcadores de infec??o e doen?a em indivíduos de área endêmica de leishmaniose visceral, em S?o Luis, MA

DOI: 10.1590/S0037-86822006000100007

Keywords: visceral leishmaniasis, immunoglobulins, infection markers.

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Abstract:

comparative study regarding igg and ige anti-leishmania as markers of infection and illness among residents of a visceral leishmaniasis visceral leishmaniasis endemic area, s?o luis, ma in the period from may 1999 to may 2000. all the 1,016 individuals younger than 16 years old were tested for the presence of igg by elisa. a total of 174 (17,1%) children revealed a positive igg test and 4 children showed symptoms of classical visceral leishmaniasis during the time of the survey: 85 ige anti-leishmania elisa tests with positivity of 43,5% were realized. in this sample, all 7 children with past-visceral leishmaniasis in the sample were igg positive and 4 (57,1%) were ige positive, even after a 7 year post treatment period. three children with current visceral leishmaniasis were evaluated, and all of them were positive for both tests. the detection of antileishman ige antibodies presented as a good marker for infection by leishmania chagasi in endemic areas but not as a disease marker.

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