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Mar 01, 2024Open    Access

Determination of Cadmium Content in Pork by Graphite Furnace Atomic Absorption Spectrometry Combined with Matrix Matching Method and Its Health Risk Assessment

Liping Chen,Weidong Zhang,Guoguang Zhang,Min Liu,Yuchao Tian,Xiaolin Wan,Fule Wang
Objective: Optimization of the method of graphite furnace atomic absorption in the existing national standard method GB 5009.15-2014 to establish the method for quantitative detection of cadmium and analyze the health risks of cadmium in pork. Methods: The temperature program of the graphite furnace was optimized and was combined with the matrix matching method. The cadmium content and health risk of pork samples from seven producing areas from 2019 to 2020 were...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111209


Aug 29, 2023Open    Access

A Detailed Review on Analytical Methods to Manage the Impurities in Drug Substances

Dharmpal Singh, Rekha Isharani
Impurities, particularly those associated with the API (active pharmaceutical ingredient) and causing deterioration or interaction, may lower a drug’s quality, safety, and efficacy. The successful reduction and control of impurities in pharmaceuticals rely on safety-based impurity limits. Many methods have been developed to define a practically safe dosage of impurities, with an emphasis on daily exposure limitations. They include permissible daily exposure (PDE), acceptable intake (AI), the thr...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110223


Aug 22, 2023Open    Access

Effect of Lignocellulose Waste-Biomass Pretreatment of the Peels of Musa acuminata (Banana) and Ananas comosus (Pineapple) on the Production of Bioethanol via Solid-State Fermentation

Nyinchuo Evate, Pride Ndasi Ngwasiri, Wilson Agwanande Ambindei, Ngwa Martin Ngwabie, Martin Benoit Ngassoum
The use of fruits both domestically and industrially generates waste from their discarded peels which may lead to environmental pollution and contamination. This work aims at evaluating the effects of chemical pre-treatment of biomass on the physicochemical properties and the effects of process parameters on the production of ethanol via solid-state fermentation. The biomass was dried, ground and subjected to chemical pretreatment using H2SO4 and NaOH. pH, total Titratable ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110130


Jul 21, 2022Open    Access

Determination and Evaluation of Minerals in Legumes Consumed in Vitória Da Conquista-BA

Dhavid Lucas Silva Santos, Maiara Souza Amorim, Monise Ribeiro Silva, Anaildes Lago de Carvalho, Marcelo Eca Rocha, Douglas Goncalves da Silva
Legumes have played an important role in traditional diets in various regions of the world because they meet the recommended dietary guidelines for healthy eating. The present study aimed to determine and evaluate the mineral composition of legumes consumed in the municipality of Vitória da Conquista-BA using optical emission spectrometry with inductively coupled plasma. Minerals, calcium, magnesium, potassium, iron, manganese and zinc were determined in samples of chickpeas, soybeans, peas and ...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108885


May 16, 2022Open    Access

An Alternative and Fast Method of Nitrite Determination in Meat Sausages Using the PhotoMetrix® Smartphone Applicative for Digitized Image Processing

Gleisson A. Almeida, Antonio J. Demuner, Daiane E. Blank, Cristiane I. Cerceau, Bianca L. Sousa, Iara F. Demuner, Marcela R. Coura, Maria J. M. Firmino, Marcelo H. Santos
Due to the potential threats of nitrite to public health and safety, in this work, we proposed, for the first time, the application of PhotoMetrix® software for the detection of nitrite in meat products. Nitrite monitoring in food matrices has been carried out by expensive analytical methods. Aiming mainly speed and cost reduction, colorimetric analysis software has been developed using digital imaging. Among them, the PhotoMetrix®, a free software based on template...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108689


Apr 12, 2022Open    Access

Quantification of Aloin in Aloe barbadensis Miller Leaf Gel and Latex from Selected Regions of Kenya

Caroline K. Nakiguli, Viola J. Kosgei, Jackson K. Cherutoi, John Odda
Aloe barbadensis Miller (A. barbadensis) has been reported for use in the traditional management of malaria in Kenya. Aloin (an anthraquinone-C-gly-coside) is one of the therapeutic molecules in Aloe species that is responsible for their antimalarial effect. However, there is no report on the aloin content of A. barbadensis leaves latex and gel from Kenya. This study, therefore, isolated and quantified aloin levels in Phosphate Buffered Saline (PBS) extracts of A. ...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108606


Mar 21, 2022Open    Access

Determination of Pesticide Residues Using QuEChERS Extraction with Inert GC-MSD Analytical Technique and Application on Seasonal Fruits and Vegetables in Pakistan

Aneeba Shuja, Humera Shafi, Ali Imran Abid, Mohammad Muntazir Iqbal, Muhammad Sajjad Khatak
Pesticide residues cause different health hazards when they are present in primary as well as secondary agricultural products. In this manuscript, an analytical method was developed and validated for the assessment of pesticide residues present in various vegetables and fruits most commonly consumed in Pakistan. Seven samples of various fresh fruits and vegetables were processed and analyzed for the detection and identification of different pesticides by using the quick easy cheap effective rugg...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108499


Jan 26, 2022Open    Access

Physicochemical Analysis and Fatty Acid Content of Chemical and Traditional Extracts of Shea Kernel (Vitellaria paradoxa) from Kwara State Nigeria

Nnenna Eberechi Ofoegbu-Chibuzo, Uche John Chukwu, Ifedi Peter Okoye
Physicochemical analysis and fatty acid content of chemical and traditional extracted shea kernel (Vitellaria paradoxa) from Kwara State Nigeria have been studied. The extraction of shea butter from shea kernel using chemical and traditional techniques as well as its physicochemical analysis reveals that both the chemical extracted shea butter (CSB) and the traditional extracted shea butter (TSB) are very similar in properties save for the odor (slightly choking nutty odor for CSB and sli...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108295


Dec 16, 2021Open    Access

Competitive Adsorption of Metal Ions on Peanut Testa (Arachis hypogaea L.) Extract Using Cation Exchange Resins

Theresa Orieji Uchechukwu, Uche John Chukwu, Onyewuchi Akaranta
Competitive adsorption of Fe2 , Ni2 , Pb2 , Cu2 and Zn2 in a multi-element solution was compared with the adsorption of the same in individual element solutions using cation exchange resins developed from modified peanut testa extract (PTE) as adsorbents. Modified PTE-polyphenols cation exchangers were prepared by first crosslinking with phosphorus oxychloride (POCl3) before functionalizing with chlorosulphonic acid (CSA). In another insta...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107575


Oct 09, 2021Open    Access

A Novel Label-Free Fluorescence Strategy Based on Dumbbell Probe for Sensitive Detection of DNA Ligase

Wenping Zhu, Xinlu Wang, Liyan Dai, Weijie Yang, Yanxia Li, Ruilan Liu
Based on the principle that DNA ligation reaction mediates hydrolysis of the dumbbell probe (DP), a novel label-free strategy for sensitive detection of DNA ligase was developed. DNA ligase ligated the nick on DP to generate a fully closed dumbbell DNA structure, which could prevent the hydrolysis of exonuclease, after combining with SYBR Green I (SG I), a strong fluorescent signal was obtained. In the absence of DNA ligase, DP was hydrolyzed into single nucleotides by exonuclease, resulting in ...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107983


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