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May 30, 2023Open Access
The rhabdoid tumor is a rare and aggressive tumor of pediatric population. Their grouping within a single entity is recent, following the discovery of a bi-allelic inactivation of the HSNF5/INI1 tumor suppressor gene in tumor cells. The present study aims to highlight the different epidemiological, clinical, histopathological, and immunohistochemical, and genetic features of extra-renal rhabdoid tumors in children. We present a case series of extra-renal rhabdoid tumor (ERRT), recorded at the De...
Mar 29, 2023Open Access
The effect of centimeter waves of non-thermal level on four types of bacteria has been studied. On E. coli strains, a sharp increase in survival during the first cycle of cell division was obtained. The mechanism of inhibition of pathogenic bacteria by a weak electromagnetic field is explained. The mechanism of stimulating the survival of bacteria associated with the activation of genes that reduces the number of dying bacteria is explained. The general form of the modified Ferhulst equat...
Mar 14, 2023Open Access
The epithelioid angiomyolipoma (EAML) is a variant of angiomyolipoma with predominant epithelioid component which has a potentially malignant behavior. We report a 40-year-old woman with the synchronous renal and hepatic epithelioid angiomyolipoma with preoperative papillary thyroid carcinoma. She had been operated to remove the tumors in her liver and kidney. The histopathological and immunohistochemical results of surgical specimens were concordant with epithelioid angiomyolipoma. Her thyroid ...
Nov 28, 2022Open Access
Objective: To analyze the BCL2 genetic as diagnostic marker among acute lymphoblastic leukemia in childhood Sudanese patients, to detect genetic polymorphism in BCL2 in childhood acute lymphoblastic leukemia patients using Polymerase chain reaction (PCR) and DNA sequencing technique to confirm the harmfulness of the detected mutation using in silico analysis. Material and Methods: Venous blood was drained by means of clean venipuncture into a labeled 5 ml K-EDTA tubes. Subsequent mixing of blood...
Nov 21, 2022Open Access
Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway (PPP) which reduces NADP to NADPH while oxidizing glucose-6-phosphate. NADPH subsequently acts as a reducing agent, allowing oxidized glutathione to be converted to reduced glutathione, which protects against oxidant damage. Objectives: This study aimed to assess G6PD activity in Sudanese diabetic patients and its relationship with hyperglycemia. Materials and Methods: This study was a case control study done ...
Oct 28, 2022Open Access
Long Covid has many symptoms that overlap with ME (myalgic encephalo-myelitis)/CFS (chronic fatigue syndrome), FM (fibromyalgia), EBV (Epstein-Barr virus), CMV (cytomegalovirus), CIRS (chronic inflammatory response syndrome), MCAS (mast cell activation syndrome), POTS (postural orthostatic tachycardia syndrome), and post viral fatigue syndrome. They all portend a “long haul” with an antioxidant shortfall and elevated Ca:Mg. Oxidative stress is the root cause. Linkage between TGF (transforming gr...
Sep 20, 2022Open Access
The calcium to magnesium ratio plus adequate vitamin D greatly determine success or not in the immune battle against pathogens and cancer, not to mention cardiovascular disease. Ionized calcium and magnesium in normal, healthy individuals can be calculated and a ratio determined from serum levels. Using widely accepted laboratory reference range values and NHANES data, the recommended daily allowances from the Institute of Medicine of the National Academy of Sciences for calcium, magnesium, and ...
Aug 29, 2022Open Access
Congenital bone malformations of the cervico-occipital hinge are rare entities. They are often asymptomatic and often incidentally discovered during imaging examinations for malformative assessment or for other indications, but they can be the cause of neurological symptoms or signs of compression in the posterior fossa. We report a case of a bony malformation of the cervico-occipital hinge in a 16-year-old girl, with no medical and surgical history or known history of trauma. This malformation ...
Aug 25, 2022Open Access
Introduction: The volumetric capnography (VCap) is a quick, simple, cheap, and effective test for distal airways. The test is based on the volumetric concentration of expired CO2 and tidal volume (CV) flow over a single exhalation. Literature Review: The exam makes it possible to observe the curve of expired CO2, considering its concentration. These CO2 curves are plotted, showing the inspired volume point by point, and the dead space volume can be calculated among the elimination of CO2 with ea...
May 27, 2022Open Access
Long Covid, now also reported in children, has become increasingly alarming. Perhaps a third of those who develop MIS-C go on to experience Long Covid. Etiology is elusive. The role of vitamin D in bone and immune health has been recognized but magnesium deficiency has escaped attention. A physiologic and biochemical argument for its culpability in Long Covid as well Chronic Fatigue Syndrome, Fibromyalgia, Epstein Barr Virus, and Cytomegalovirus is discussed.
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