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May 22, 2018Open    AccessArticle

Estimation of Clinical, Immunological and Virological Failure of First Line Antiretroviral Treatment in Kinshasa, Democratic Republic of Congo

Erick Ntambwe Kamangu
Background: The prevalence of Human Immunodeficiency Virus (HIV) infection was 1.2% in the Democratic Republic of Congo, according to the Demographic Health Study report in 2014. In 2012, the severe failure rate to first-line ART in Kinshasa was estimated at more than 16%. Objective: The objective of this study is to determine the rate of clinical, immunological and virological failure in first-line treatment

May 21, 2018Open    AccessArticle

Sociodemographic and Anthropometric Profile of Positive HIV Patients in Early Traditional Treatment: Case of the Bonkoko Center

Ben Ilunga Bulanda, Elvis Tshunza Kateba, Berry Ikolango Bongenia, Victor Nyiama Kasongo, Micheline Abiba Kingombe, Erick Ntambwe Kamangu
Context: In the Democratic Republic of Congo (DRC), the Antiretroviral (ART) drug coverage is still very low throughout the country. Hence, a large number of People Living with HIV (PLHIV) use traditional treatment made from plants to fight the HIV infection and the opportunistic infection associated to it. Objective: The objective of this work was to evaluate the clinical parameters; para clinical and socio-demographic studies at

Mar 30, 2018Open    AccessArticle

Knowledge, Attitude, Practice of the Kamina City Population in the Democratic Republic of Congo on Voluntary Screening of HIV/Aids

Ilunga Masuku Anany
HIV/AIDS infection, although of particular gravity in developing countries, today affects all countries of the world. Among the means used to combat this pathology is voluntary testing, which is both an effective and economical strategy for facilitating behavior change. This study allowed us to contribute to the improvement of the knowledge, attitude and practice of the population on voluntary HIV/AIDS testing. This is a cross-sec

Jul 27, 2017Open    AccessArticle

Incidence and Fetal Outcomes of HIV/Aids Patients at Hasan Sadikin General Hospital

Anita Rachmawati, Johannes C. Mose, Hasan Sadikin
Introduction: The increasing number of HIV/AIDS incidence over time begins to become global problems. One of the current concerns is the morbidity and mortality rates in the fetal outcomes patients with HIV/AIDS who can provide many complications. The importance of adequate pre-and antenatal care may help to reduce morbidity and mortality due to this condition. The purpose of this study is to determine inciden

Feb 04, 2017Open    AccessArticle

Correlation between Sequencing Results from Liquid Plasma and Dried Plasma Spot (DPS) for Determination of HIV Type 1 Non-B Subtypes

Erick Ntambwe Kamangu, Adawaye Chatté, Dolores Vaira, Patrick de Mol, Georges Lelo Mvumbi, Richard Lunganza Kalala, Marie-Pierre Hayette
Background: The blotting paper is an alternative to the collection of blood in the tubes for analysis, especially in the field of Human Immunodeficiency Virus infection. This technique allows to easily send the collected samples to specialized laboratories while limiting the stresses of storage and transport. Objective: The objective of this study was to compare the results of sequencing performed on liquid plasma and Dried Plasma

May 06, 2016Open    AccessArticle

Immunological, Virological, Parasitic and Biological Profile of Malaria/HIV Co-Infection in 18 Years Old and Above Patients in Lubumbashi (DR Congo)

Christian Kakisingi, Olivier Mukuku, Michel Manika, Augustin Mutombo, Eric Kasamba, Beya Tshikuluila, Paul Mawaw, Claude Mwamba, Oscar Luboya
Introduction: Malaria infection and HIV infection are major public health issues in several parts of the world. Together they have caused more than a million deaths per year. Africa, and Sub-Saharan in particular are the most affected. Our study objective is to determine the prevalence of Malaria/HIV co-infection and describe its immunological, virological, parasitic and biological characteristics. Methodology: This is a descriptive, transversal and multi centric study done on 18 years old and a...

Jun 12, 2015Open    AccessArticle

Concept Analysis: Engagement in Personal HIV Management

Matt L. Pimentel
A concept analysis is an endeavor in social sciences to ensure proper usage of the term among researchers, theorists, and practitioners. The concept of engagement has recently been touted as the term describing HIV-infected individuals who are compliant with their highly active antiretroviral therapy (HAART) medications. Accordingly, engagement has also come to mean that the full compliance with not just HAART, but also compliance with lab tests, medical visits, and counseling services. Post-rel...

Jun 08, 2015Open    AccessArticle

Virological Profile of Patients Infected with HIV Starting Antiretroviral Treatment in Kinshasa

Erick Ntambwe Kamangu, Ben Ilunga Bulanda, Berry Ikolango Bongenia, Huguette Tshweka Botomwito, Georges Lelo Mvumbi, Patrick De Mol, Dolores Vaira, Marie-Pierre Hayette, Richard Lunganza Kalala
Background: Viral Load (VL), CD4 T cells count and clinical signs are significant parameters for the decision of starting ARV Treatment (ART). The aim of this study is to determine the Viral Load profile of eligible patients on treatment in the centers according to the algorithm used in Kinshasa and the DRC. Methodology: Our sample consisted of 153 HIV-positive patients naive of ART. All patients aged over 18 years were included in the study without gender discrimination. The determination of th...

Mar 20, 2015Open    AccessArticle

Comparison of an In-House Quantitative Real-Time PCR and COBAS AmpliPrep/TaqMan Roche for Determination of Viral Load for HIV Type 1 Non-B

Erick Ntambwe Kamangu, Adawaye Chatte, Raphael Boreux, Fabrice Susin, Richard Lunganza Kalala, Georges Lelo Mvumbi, Patrick De Mol, Marie-Pierre Hayette, Dolores Vaira
Context: The in-house techniques or experimental methods are increasingly recommended for their low-cost reagents for the determination of the Viral Load (VL) in resource-limited settings. The objective of this study was to compare the determination of VL from HIV-1 non-B samples by an in-house technique with the COBAS AmpliPrep/TaqMan version 2.0. Method: In this cross-sectional study, 39 plasma samples from patients infected with HIV type 1 non-B from N’Djamena and Kinshasa were used to determ...

Feb 12, 2015Open    AccessArticle

Prevalence of Malaria Infection among People Living with HIV in Kinshasa

Erick Ntambwe Kamangu, Hypolite Mavoko Muhindo, Carole Weba Wapa-Kamangu, Hip-polyte Nani-Tuma Situakibanza
Background: Infection with the Human Immunodeficiency Virus (HIV) and malaria are two infectious diseases which are among the leading causes of morbidity and mortality in Sub-Saharan Africa and each a major public health problem. Data on malaria infection among people living with HIV (PLHIV) are poorly defined in Kinshasa as there are very few studies available on the subject. Objective: To determine the rate of co-infection HIV/malaria in Kinshasa to improve the care of PLHIV, this study was in...