%0 Journal Article
%T Hypovitaminosis E and Endometriosis in a Sub-Saharan Population
%A Monzango Sibo
%A Esimo Mboloko
%A Lobota Mputu
%A Itewa Monka
%A Mayoka Mamoi
%A Naomie Amba
%A Ntanga Kabuya
%A Cl¨Śment Ferrier
%A Maxime Fastrez
%A Darai Emile
%A Sendeke Mogwo
%A Jean-Claude Mulunda
%J Open Access Library Journal
%V 10
%N 9
%P 1-15
%@ 2333-9721
%D 2023
%I Open Access Library
%R 10.4236/oalib.1110485
%X Endometriosis is a chronic gynecological condition defined by the presence of endometrial-like tissue outside the uterus affecting approximately one in 10 women worldwide. Endometriosis is source of chronic pelvic pain and infertility and represents a significant economic burden. This study aims to determine the frequency of hypovitaminosis E in sub-Saharan women in Kinshasa with endometriosis and identify associated risk factors. A case-control study of 244 patients undergoing a laparoscopy in 8 Kinshasa medical centers between January 2019 and October 2022. Among these, 82 women with endometriosis (cases) and 164 women with a normal pelvis (controls) were matched in age function. Chi-square tests and t-tests were used to compare these two groups. A multivariate logistic regression was performed to identify risk factors related to endometriosis. Hypovitaminosis E in women with endometriosis was 74.39%. Dysmenorrhea (OR 24.234 [95% CI: 12.141 - 50.026)], p < 0.001), nulliparity (OR 5.157 [95% CI: 2.458 - 10.819], p < 0.001), history of unsafe abortion (OR 8.389 [95% CI: 4.277 - 16.476], p < 0.001), infertility (OR 5.157 [95% CI: 2.458 - 10.819], p = 0.02), early menarche (OR 28.830 [95% CI: 13.640 - 60.933], p < 0.001) and hypovitaminosis E (OR 4.538 [95% CI: 2.523 - 8.161], p < 0.001 were identified as risk factors. Use of oral contraceptives (OR 0.188 [95% CI: 0.093 - 0.381], p < 0.001) had a protective factor against endometriosis. Despite some limits, our data underline the role of vitamin E deficiency as a potential factor of endometriosis in a sub-Saharan population especially subject to deficiency intake.
%K Endometriosis
%K Risk Factors
%K Sub-Saharan Women
%K Hypovitaminosis E
%K Unsafe Abortion
%U http://www.oalib.com/paper/6800666