%0 Journal Article
%T Antibiotic Resistance and Phynotypic Detection of AmpC Beta-Lactamase Producing <i>Escherichia coli</i> from Urine of Students Attending Fulafia Clinic
%A Usman S. Okposhi
%A Kabiru A. Shuaibu
%A Chuku Aleruchi
%A Fatima A. Yusuf
%A NajaˇŻatu S. Hadi
%J Open Access Library Journal
%V 9
%N 7
%P 1-10
%@ 2333-9721
%D 2022
%I Open Access Library
%R 10.4236/oalib.1108550
%X <i>Escherichia coli</i> also known as <i>E. coli</i> are gram-negative facultative anaerobic, rod-shaped, Coliform bacteria, commonly found in the lower intestine of warm-blooded organisms. This study was designed to determine the antibiotic susceptibility and the phenotypic detection of AmpC beta-lactamase producing <i>Escherichia coli</i> from the urine of students attending FuLafia Clinic, Nasarawa State, Nigeria. A total of 22 urine samples were collected from the students. Eleven (50%) <i>Escherichia coli</i> isolates were recovered and identified by standard Microbiological methods. The antibiotic susceptibility of <i>Escherichia coli</i> from the urine of students showed that the isolates were susceptible to gentamycin (27%), streptomycin (22.7%), chloramphenicol (18%), sparfloxacin (13.6%), tarivid (9%), augumentin and septrin with (4.5%) each, while none was susceptible to amoxicillin/clavulanic acid, pefloxacin and ciprofloxacin respectively. The <i>E. coli</i> isolated from the urine of the students showed varying antibiotic-resistant phenotypes with SXTCH-SP-CPX-AM-AU-CN-PEF-OFX-S as the most common; with a percentage occurrence of 27.3%. The commonest Multiple Antibiotic Resistance indexes (MAR) of these isolates was 0.9 and the frequency of occurrence was 11 (50%). The <i>E. coli</i> isolated from the urine showed that 5 (45.5%) were resistant to cefoxitin, as 3 (60.0%) out of which were confirmed to be AmpC beta-lactamase producing <i>E. coli</i>.
%K Urine
%K Escherichia coli
%K Antibiotic
%K AmpC
%K Beta-Lactamase
%U http://www.oalib.com/paper/6771141