%0 Journal Article
%T Bioactive Constituents of Methanol Extract of Xylopia aethiopica (UDA) Fruits from Nsukka, Enugu State, Nigeria
%A Innocent Uzochukwu Okagu
%A Uchenna Ekpereamaka Ngwu
%A Chinyere Jane Odenigbo
%J Open Access Library Journal
%V 5
%N 3
%P 1-11
%@ 2333-9721
%D 2018
%I Open Access Library
%R 10.4236/oalib.1104230
%X
The bioactive compounds in
methanol extract of Xylopia aethiopica fruits were determined using a combination of gas chromatography and mass
spectrometry (GC-MS). The compound identification was based on the molecular
structure, molecular mass and calculated fragments. Interpretation on mass
spectrum of GC-MS analyzer (Hewlett Packard GC-MS system) was done using the
database of National Institute Standard and Technology (NIST). The results
showed different peaks representing the presence of about 58 bioactive
compounds which are mainly carboxylic acids, esters, phenolic compounds and
fatty acids. The most abundant bioactive compounds detected were 2,4,6-octatriene (2.74%),
cyclohexanemethanol (2.57%), kaurene (3.59%), 9,12-octadecadienoic acid
(5.63%), 1,6-cyclodecadiene (10.81%), terpineol (3.22%), cyclohexene (3.32%), copaene
(3.04%), 1,6-cyclodecadiene (5.53%), 1-hexadecyne (5.63%) and silane (4.63%).
The presence of these bioactive components suggests that the extract is of
great pharmaceutical value.
%K Xylopia aethiopica
%K Bioactive Compounds
%K Gas Chromatography
%K Mass Spectrometry
%K Methanol Extract
%U http://www.oalib.com/paper/5292186