%0 Journal Article
%T A Case Crossover Analysis of Out-of-Hospital Cardiac Arrest and Particulate Matter Air Pollution: Investigation of Specific Subgroups
%A Marie Albert
%A Mohamed Lemdani
%A Damien Cuny
%A Patrick Duriez
%A Jos¨¦phine Escutnaire
%A Pierre-Yves Gueugniaud
%A Eric Wiel
%A Herv¨¦ Hubert
%A Christophe Di Pompeo
%J Open Access Library Journal
%V 4
%N 12
%P 1-14
%@ 2333-9721
%D 2017
%I Open Access Library
%R 10.4236/oalib.1104143
%X
There is increasing evidence of association between
particulate matter air pollution and cardiovascular mortality and morbidity.
However, the association with the out-of-hospital cardiac arrest (OHCA) event
is less clear. We investigated the effects of short-term particulate matter
exposure on OHCA especially among specific subgroups. The study included
OHCA that occurred in the Nord-Pas-de-Calais region, France, in 2015. A
time-stratified case-crossover
study design coupled with a conditional logistic regression was used to
evaluate the association between OHCA and particle levels of 10 or 2.5
micrometers or less (PM10 or PM2.5 respectively) measured within the hour of
the arrest up to 5 days before. Susceptible subgroups by sex, age, diabetes
status among OHCA that occurred during non-holiday periods were investigated. In all, 1039 cases were included. Significant associations were found
between OHCA during non-holiday periods and PM2.5 and PM10 exposure four days
before the arrest and on the day of the arrest. The largest OR were found for
the cumulative average twelve hours before the arrest of PM2.5 (OR = 1.17, p = 0.016)
and PM10 (OR = 1.33, p < 0.001). With PM2.5, larger OR with smaller p-values
were generally obtained within the subgroups of men, age 50 to 75 years old and
cases with diabetes. The findings show a significant link between
short-term exposure to particulate matter and OHCA during non-holiday periods,
with susceptible subgroups to PM2.5 (men, age 50 to 75 years old and
diabetics).
%K Sudden Death
%K Heart Arrest
%K Epidemiology
%K Particulates
%K Pollution
%U http://www.oalib.com/paper/5291470