Six new provitamin A hybrids (LY1001-14, LY1001-22 and LY1001-23,) and synthetic maize varieties (PVASYN13, PVASYN9 and PVASYN7) were tested for their agronomic performance and compared to a locally adapted improved open pollinated variety (SAMARU) in the central and western conditions of DRC. A randomized complete block experiment with four replications was used. Following data were collected: 50% male and female flowering, plant and ear aspect, diseases incidence, plant height, ear aspect, ear rot and yield. The results showed non-significant differences (p > 0.05) in disease incidence and ears rot. Significant differences were observed (p < 0.05) for number of days to 50% of male and female flowering, anthesis-silking interval, plant height, plant aspect, ear aspect, and yield. For yield, two hybrids (LY100-14 and LY1001-22) respectively out-yielded local check by 71% and 56% while one synthetic (PVASYN 9) out-yielded the local check by 31% and the two others were comparable to the local check. Thus the hybrids (LY100-14 and LY1001-22) and synthetic varieties (PVASYN 9 and PVASYN13) are ready to be recommended for release to contribute to better production and nutrition for vulnerable people.