%0 Journal Article %T A New Dolabrane Dinorditerpene from Ceriops tagal %A Xin Wu %A Hongbo Liao %A Hongyu Lu %A Chaohua Zhang %J Open Access Library Journal %V 3 %N 8 %P 1-6 %@ 2333-9721 %D 2016 %I Open Access Library %R 10.4236/oalib.1102957 %X
A new dolabrane dinorditerpene, tagalsine X(1), was isolated from the leaves of Ceriops tagal, along with five known analogues (2-6). Their structures were established on the basis of spectroscopic data or comparison with the literatural data. Their cytotoxic activities against four human carcinoma cell lines (CNE-2, HCT-116, HepG2and A549) were also evaluated, which displayed that only compound 2 had significant cytotoxicity against those cell lines with IC50 values of 13.57, 42.32, 11.21 and 15.23 ¦ÌM, respectively.
%K Ceriops tagal %K Dolabrane %K Tagalsine X %K Cytotoxicity %U http://www.oalib.com/paper/5271994