%0 Journal Article
%T ˇ°Natural Site-Directed Mutagenesisˇ± Might Exist in Eukaryotic Cells
%A Gao-De Li
%J Open Access Library Journal
%V 3
%N 4
%P 1-5
%@ 2333-9721
%D 2016
%I Open Access Library
%R 10.4236/oalib.1102595
%X Site-directed mutagenesis refers to a man-made molecular biology method that
is used to make genetic alterations in the DNA sequence of a gene of interest. But
based on our recently published experimental findings, we propose that ˇ°natural
site-directed mutagenesisˇ± might exist in eukaryotic cells, which is triggered by
harmful agents and co-directed by special transcription hotspots and mutation-contained
intranuclear primers.
%K Natural Site-Directed Mutagenesis
%K Genetic Alteration
%K Mutation
%K CAGFs
%K DNA to DNA Transcription
%K Drug Resistance
%K Evolution of Eukaryotes
%K Antibody Diversity
%K Somatic Hypermutation
%U http://www.oalib.com/paper/5264813