%0 Journal Article
%T Antiestrogenic Compounds and Breast Cancer
%A Muhammad Asim
%A Noman Ali
%A Raheel Asghar
%A Awais Amin
%A Muhammad Saif Ur Rahman
%J Open Access Library Journal
%V 3
%N 3
%P 1-11
%@ 2333-9721
%D 2016
%I Open Access Library
%R 10.4236/oalib.1102468
%X Breast cancer is the main threat around the world. Estrogen and estrogen
receptors (ER) assume a noteworthy part in breast disease movement and
advancement. Breast cancer is the most pervasive disease in women, every year
more than 200,000 new cases analyzed. Estrogen receptors are expressed in 70%
of all the breast cancer cases, so it is an important target for the treatment
of breast cancer. Anti-estrogen compounds are of significant importance since
it can be used as a therapy for breast cancer. In this review we have
summarized the most important anti-estrogen compounds being used for the
treatment of the breast cancer and their related molecular pathways with the
hope that this will enhance our understanding to these compounds.
%K Breast Cancer
%K Anti-Estrogen Compounds
%K Bcl-2
%K GRP78
%K Caspase 8
%U http://www.oalib.com/paper/5263044