%0 Journal Article
%T Late Onset Neonatal Herpes Encephalitis: A Case-Based CNS Complication and Neurological Outcome
%A Surya N. Gupta
%A Vikash S. Gupta
%A Nirali Borad
%J Open Access Library Journal
%V 2
%N 2
%P 1-7
%@ 2333-9721
%D 2015
%I Open Access Library
%R 10.4236/oalib.1101280
%X Individual neurological complication caused by Herpes simplex viruses in neonates
is well-known. We report neonatal Herpes encephalitis that caused multiple neurological
complications in the same patient during acute phase of illness. Our patient differs
from previously reported cases in the following ways: 1) Late onset neonatal presentation;
2) Development of multiple neurologic complications during acyclovir therapy; 3)
Cesarean-section did not prevent perinatal transmission of Herpes simplex virus;
and 4) Our patient¡¯s acute hydrocephalus was managed conservatively and he had no
reoccurrence of seizure, hydrocephalus, and no motor deficits. A high degree of
suspicion, timely needed supportive medical and surgical care, and prompt initiation
of intravenous acyclovir offer the best chance for neurological outcome in neonates
with Herpes encephalitis.
%K Neonatal Herpes Encephalitis
%K Central Nervous System Complication
%K Acute Hydrocephalus
%K Intracranial Hemorrhage
%K Opsoclonus or Dancing eye
%K Cerebral Palsy
%U http://www.oalib.com/paper/3134488