%0 Journal Article
%T Optimization of the Extraction Technology of Chlorogenic Acid in Honeysuckle Response Surface Method
%A Tingting Cui
%A Chao Wang
%A Changsong Shan
%A Peng Wu
%J Open Access Library Journal
%V 1
%N 6
%P 1-9
%@ 2333-9721
%D 2014
%I Open Access Library
%R 10.4236/oalib.1100941
%X The ultrasound-assisted extraction of chlorogenic acid from honeysuckle
was modeled using response surface methodology. A three-level-three-factor
Box¨CBehnken design was employed to optimize three extraction variables,
including extraction temperature (X<sub>1</sub>), ethanol concentration (X<sub>2</sub>),
and soak time (X<sub>3</sub>), for the achievement of high extraction yield of
the chlorogenic acid. The optimized conditions are extract temperature of 80¡æ,
ethanol concentration of 70.37%, soak time of 9.35 h. Under this optimized conditions,
the experimental yield of chlorogenic acid is 1.918%, which is well matched
with the predicted yield of 1.929%.
%K Design-Expert Software
%K Lonicera Japonica
%K Chlorogenic Acid
%K Extraction Technology Optimization
%U http://www.oalib.com/paper/3104659