%0 Journal Article %T Gestational Hypervolemic Hypertension Is Clinically Different from ˇ°Classicalˇ± Preeclampsia %A Eszter Hantosi %A Zsolt Ifi %A S¨˘ra Jeges %A J¨®zsef B¨®dis %A P¨¦ter Tam¨˘s %J Open Access Library Journal %V 1 %N 4 %P 1-4 %@ 2333-9721 %D 2014 %I Open Access Library %R 10.4236/oalib.1100751 %X

Objective: Homogenous pathogenesis of preeclampsia has been challenged. We examined the clinical characteristics of preeclamptic patients with discordant fetal growth which is one of the controversial issues in preeclampsia. Methods: Clinical index values including central hemodynamics of third-trimester preeclamptic patients with distinct fetal birth weights (group A: birth weight ˇÝ 50th percentile; n = 23 and group B: birth weight < 50th percentile; n = 14) were compared. Results: Pregnant women of group A were characteristically obese and edematous, but no fetal complications were observed. Patients of group B were younger, onset of preeclampsia was earlier, proteinuria was more severe, and fetal compromise was frequent. A marked difference between the two groups was noticed in central hemodynamics as the mean of CO (cardiac output) was 8.5 and 5.6 l/min in group A and B, respectively (p < 0.001). CO of less than 7.45 l/min was found to be associated with fetal birth weight below 50th percentile (OR = 15.6; 95% CI: 3.2 and 45.8, p = 0.001). Conclusions: Augmented CO in pregnancy may ensure efficient placental blood supply, but it may cause hypertension with subsequent moderate proteinuria. This condition, however, seems to be different from the ˇ°classicalˇ± preeclampsia.

%K Preeclampsia %K Distinct Birth Weights %K Distinct Hemodynamics %U http://www.oalib.com/paper/3099387