%0 Journal Article
%T Urinary Anomalies in Fetus with Neural Tube Defects
%A Suelen F. Costa
%A Helce R. Julio-Junior
%A Fabio Bernardo
%A Francisco J. B. Sampaio
%A Luciano A. Favorito
%J Open Access Library Journal
%V 1
%N 6
%P 1-6
%@ 2333-9721
%D 2014
%I Open Access Library
%R 10.4236/oalib.1100734
%X Background: The objective
of this study is to analyze the incidence of congenital urogenital malformations
in human fetuses with neural tube defects (NTDs). Methods: We studied 320 human
fetuses (214 males and 106 female) ranged in age from 12 to 35 weeks
post-conception (WPC). The fetuses were carefully dissected with the aid of a
stereoscopic lens with 16/25กม magnification. The
abdomen and pelvis were opened to identify and expose the urogenital organs. We
studied the incidence of renal, ureteral, bladder, urethral, testicular,
epididymal, vas deferens, prostate and penile and uterine anomalies. The renal
anomalies were divided into rotation, fusion, number and ascension. We observed
the presence of seminalvesicle and ureteral duplication, bladderseptation,
hypospadias and posterior urethral valve. Results: We observed 17 fetuses
(5.31%) with NTDs ranged in age between 18 to 34 WPC, weighted between 170 and
2325 g, and had crown- rump length between 13 and 34 cm. Of the 17 fetuses, 4 (23.4%)
presented some kind of anomaly of the urogenital system. Renal anomalies were
found in three fetuses (17.6%) and a duplication of the left ureter in one
fetus (5.8%). We do not observe anomalies in genital organs in this sample. Conclusions:
We concluded that the urogenital anomalies in human fetuses with neural tube defects
are significant with an incidence superior a 20%. In this study we have not
found severe urogenital anomaly that causes damage of the body function.
%K Neural Tube Defects
%K Urinary System
%K Genital System
%K Embryology
%U http://www.oalib.com/paper/3099333