%0 Journal Article %T Role of Trace Elements Alzheimer¡¯s Disease %A Sanjeev Kumar %A Reena Mittal %A Shweta Chaudhary %A Deep Chand Jain %J Open Access Library Journal %V 1 %N 6 %P 1-30 %@ 2333-9721 %D 2014 %I Open Access Library %R 10.4236/oalib.1100714 %X
Atomic
absorption analysis involves measuring the absorption of light by vaporized
ground state atoms and relating the absorption to concentration. The incident
beam of light is attenuated by atomic vapour absorption according to Beer¡¯s
Law. The estimation of trace elements shows a colorful presentation of
different metals. It has been seen and found that the levels of zinc, calcium,
magnesium, aluminum are lower in Alzheimer¡¯s disease samples in comparison to
healthy controls. The elements such as copper, iron, potassium and sodium were
found higher than controls. A statistical analysis has been applied and
measured regression with correlation coefficients including multiple
correlation coefficients between different trace elements like Na, K, Ca, Mg,
Zn, Cu, Fe and Al in normal samples. A trend has been found in coefficient of
correlation such aswith positive correlation and with negative correlation. Coefficient of
partial correlation is also calculated and found that a trend has been set up
between trace elements and given here as with positive correlation and with negative correlation. Multiple correlation coefficient in normal
healthy person has been estimated and found that a trend, which is given here
as. Multiple
correlation coefficient in AD samples has been estimated and found that a
trend, which is given here as .